Hi, For last 2 weeks (short time i know) CFS has completely abated. No symptoms. Zero. Zilch. I know its an early post but if it can help one person more, its worthwhile. I have been sufferer 5 years, at times bedridden. I never had a period that faintly resembled this. I have wrote extensively about my success with amino acids that help my symptoms tremendously and it was impossible to do without them when i crashed in past. I used to think that using high dose arginine that was related to NO, as Fluge and Mella previously hypothesised. I am pretty sure now that is not the case, that the body was soaking it up as alternative fuel when PDH pathway is interrupted. Reason being, I get same relief in high doses of glutamine, TMG or carnitine. My serum glutamine and glycine levels were very low in past, supporting the research in amino acid traits in male v female. This recent recovery has coincided with me starting Vit d (25k), vit e (400ui) and Equilibrant X 6 day. I haven't used amino in 2-3 weeks. To what supplement do i owe this sudden purple patch, I am not sure. Backed into a corner would go with equilibrant. I used equilibrant in past when i was pretty bad and seemed to help marginally. But now i added it when I was fairly decent (maybe a 80/100) and seems to have propelled me to the dizzy heights of normality. Have CFS long enough to know that one swallow does'nt make a summer, so will tentatively enjoy it for now. Any questions, feel free.