Definitely.
My problems probably stemmed from mercury and candidiasis originally, then infections, autoimmunity...so my plan, if I use Sanum, would be for addressing candidiasis as adjunct to some other things, as others have suggested.
Can you say anything more about the bad reactions you got and what you would do differently now?
This is a bit complicated and probably not what you were looking for but I'll give it a go.
I developed redox instability alongside PEM and an ME/CFS diagnosis back in 2006. So what is redox instability you might ask?
In his 2009 Fairfax lecture Paul Cheney claimed a redox problem was central and universal in ME/CFS. He stated there were many treatments that were consistently 'bad' and worsened the problem for all people suffering with this such as MB12, CoQ10, vitamin D, etc. He also stated there were a few that were universally 'good'. He backed this up by gauging response to these substances in real time with an echo machine. Though his findings weren't popular in our community, they lined up perfectly with my experiences with the substances.
If I'd take any of the 'bad' substances, as well as others I concluded were no good
including the Sanuvis, I'd become overly stimulated and I'd switch into anaerobic metabolism. It would feel great to have near-normal energy for several hours, but I'd be using up whatever reserve energy I had (probably glycogen). I'd have to wait another two days to replenish these stores and get another boost. If I tried the very next day I'd become overwhelmed by oxidative stress and all my symptoms would get worse. The glucose energy was coming in to back up the system which was failing due to oxidative stress. So I concluded this feature was, as Cheney stated, the result of the central energy problem in this disease.
Interestingly I regained redox stability within a few days of practicing extreme avoidance down in Death Valley. Presumably it was mycotoxins and/or other ambient inflammatory biotoxins I was avoiding. So the linchpin of my illness appeared to be a reaction to biotoxins. Cheney has come to acknowledge biotoxin illness, CIRS as Shoemaker diagnoses it, is indistinguishable from ME/CFS and that he and Shoemaker often swap patients. I presume all Cheney's patients who'd eventually be deemed to be suffering from CIRS were also checked on his echo machine when they saw him, ensuring they also had the energy problem. So cure the CIRS and you cure the energy problem Cheney believes to be at the center of this disease.
I also learned my babesia duncani infection has been amplifying my disease, including the redox problem, making me a whole lot worse. I'm pretty sure it's a toxin that the pathogen is releasing that's causing an enormous amount of oxidative stress and acidification. Dealing with this bug has been tricky. When it goes well, it's great and the gasoline is taken off the fire but I can't sustain this at the moment.
I'm now living in a house with much better air. and I'm using binders such as cholestyramine, activated charcoal, chlorella, etc to pull many years worth of stored toxin from my system. I'm also trying to get on top of the babesia but my immune system is so messed up that it's going to likely take some extreme measures to accomplish this. The other intervention that's working for me is following a slightly adapted version of the diet recommended by Biological Medicine practitioners. I've found this is a surefire way to turn down the inflammation in the system that has such a negative effect on terrain; the terrain that bugs love and are most pathogenic in. So I try to keep my protein consumption below 100g/day, and I've cut out mammalian meats and other highly acidifying protein. Just doing this has simulated most of the benefit of dealing with the babesia infection: it takes the gasoline away. As I've said in other posts, I now believe this is a really important part of getting well. We're too sick and have too many bugs to kill without modifying the terrain.
So to sum it up: biotoxins produce inflammation central to my disease that is made far worse by the oxidative stress caused by a reaction to some sort of babesia toxin and is then further amplified by a high acid diet. Biological Medicine didn't stand much of a chance with all these things impinging on my terrain. It might when I manage to put it all together.