ahmo
Senior Member
- Messages
- 4,805
- Location
- Northcoast NSW, Australia
This is a new symptom for me. I've had a small blueish 'lesion' at the corner of my lip for some time (years?), which spontaneously blew up into a blood blister a few months ago. It then retreated back to its former barely noticeable size. Now during the past month I've had 3 more eruptions. 2 were inside my cheek, recurring at the same place, and most recently one on the side of my tongue. After about 2 days they have resolved into what looks like a deflated blister, and then disappeared.
I've been researching Mast Cell syndrome, which I'm pretty sure accounts for my very blotchy skin, but for which a definitive diagnosis is bone marrow biopsy, which is not going to happen. In my searching I've wondered if these blisters are related to mast cell. There's another thing called mucous membrane pemphigoid, "Mucous membrane pemphigoid (MMP) is an autoimmune blistering disorder that is characterized by subepithelial bullae" or Angina Bullosa Haemorrhagica, "Differential diagnosis must include pemphigus, bullous pemphigoid, bullous lichen planus, dermatitis herpetiformis, epidermolysis bullosa, oral amyloidosis and thrombocytopenia. No treatment is required for ABH because the blood blisters spontaneously rupture and heal." "A causative factor is not identified in almost 50% of patients." "MMP is not a single disease, rather it represents a group of heterogeneous, chronic subepithelial blistering diseases that primarily affect mucosal surfaces..."
Anyone have experience or understanding of this? What really concerns me is that these are suddenly occurring, and recurring. The first one in my mouth I thought might have been an injury from eating a hard nut. But not the following ones. This is happening at the same time as all my other symptoms are reducing, and there's been no change in my diet, few changes in my supps. Thanks for any input. ahmo
I've been researching Mast Cell syndrome, which I'm pretty sure accounts for my very blotchy skin, but for which a definitive diagnosis is bone marrow biopsy, which is not going to happen. In my searching I've wondered if these blisters are related to mast cell. There's another thing called mucous membrane pemphigoid, "Mucous membrane pemphigoid (MMP) is an autoimmune blistering disorder that is characterized by subepithelial bullae" or Angina Bullosa Haemorrhagica, "Differential diagnosis must include pemphigus, bullous pemphigoid, bullous lichen planus, dermatitis herpetiformis, epidermolysis bullosa, oral amyloidosis and thrombocytopenia. No treatment is required for ABH because the blood blisters spontaneously rupture and heal." "A causative factor is not identified in almost 50% of patients." "MMP is not a single disease, rather it represents a group of heterogeneous, chronic subepithelial blistering diseases that primarily affect mucosal surfaces..."
Anyone have experience or understanding of this? What really concerns me is that these are suddenly occurring, and recurring. The first one in my mouth I thought might have been an injury from eating a hard nut. But not the following ones. This is happening at the same time as all my other symptoms are reducing, and there's been no change in my diet, few changes in my supps. Thanks for any input. ahmo