https://www.selfhacked.com/blog/lipopolysaccharides/
CFS shows higher levels of LPS and LPS causes fatigue. This
might be due to the inflammation caused by LPS and it's effect on mitochondria.
There are some herbal formulas which have anti-inflammatory effects which reduces the effects of LPS:
Cissus Quadrangularis is one but it does seem to have sedating effects so I doubt it's value.
Other herbal formulas with effects against LPS and inflammation:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662831/
There are most likely many more herbs with LPS binding properties.
One way is to take activated charcoal, it absorbs toxins in the gut. I take 2.5 grams every day on an empty stomach. Another way, I just heard a functional medicine doctor say this on a webinar the other day.
Is to take apple pectin. It activates something in the gut that helps the gut to heal as well as absorbs LPS, if I remember right.
I doubt that is true because it is an infection which is causing all the problems and pectin will not have any effect on the infection(s) therefore it is a fanciful idea that pectin will heal the gut. It is far more difficult than that.
is charcoal constipating? I've taken it, and it seemed like it was, but v hard to tell..
good to know! that's one thing I haven't tried yet

does it also help w constipation?
Constipation in CFS and many other conditions is caused by low levels of acetylcholine resulting from insufficient choline due to dramatically high detox demands caused by Increased Digestive Permeability. The liver needs so much choline for detox that there is insufficient left for acetylcholine production ie detox takes precedence. Unfortunately supplementing Choline can cause problems in CFS due to high levels in the brain. Anything but small amounts, insufficient to meet my bodies needs, causes tiredness and sleepiness. I can manage about 200mg of Choline Bitartrate which is a tiny amount of Choline, only around 41% off the top of my head.
Choline is anti-dopaminergic and often makes undermethylated patients worse.
Taking choline with acetyl l carnitine is meant to help promote acetylcholine production but chances are that the choline will still be used up for detox purposes and not help a great deal unless you can tolerate large quantities to make up for the deficit.