I’ve noticed that my mood drops when I’m upright (sitting, standing, doing chores) long enough. I get irritable, anxious and depressed, but when I lie down my mood gets better quickly. I wonder if it has to do with OI and decreased blood flow to the brain. Do you guys experience this symptom? I was diagnosed with depression almost ten years ago but I feel like I’m not depressed anymore, I just get these weird mood fluctuations.