Dr Chia found that if you are a responder to oxymatrine, you may need go through the storm to get to the calm of better health on the other side. And after passing through the storm, Dr Chia found that you may have to keep taking the oxymatrine in order to maintain your gains. If you stop taking oxymatrine at that point, then your ME/CFS symptoms may return. That has been Dr Chia's experience.
However, if you did stop taking it and got worse again, in most cases (but not all), Dr Chia found that starting a second course of oxymatrine again led to an improvement in symptoms. But in some cases, you don't get a second chance (ie, the oxymatrine does not work the second time).
I went through the Equilibrant formula and wasn't impressed. It seems to be a mix of apoptosis stimulators (Oxymatrine/Sophros, Shitake mushroom) and apoptosis inhibitors (Vit D, A, olive leaf extract, oxymatrine effect on caspase-3) along with antivirals (olive leaf extract) to reduce viral reproduction. Apoptosis is a tricky process to activate when you have strong viral inhibitors at work and it makes no sense to include apoptosis inhibitors in the formula. I decided to avoid it and hand select better supplements to try that don't have these problems and should give a better response. His response wasn't that great anyway, it took a year of treatment and people backslid if they stopped the supplement. No wonder it isn't that popular.