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Hi! I have a single MTHFR mutation (SNP rs1801133 A/G; rs1801131 T/T), folate levels: 2.7 low↓ (range 3-17), active B12 normal 77 (range 25-165). I've been on a very restricted diet for over a year due to vitamin A overload in the past, and react badly to vitamin A and carotene-rich foods. My most noticeable issues at the moment are:
severe fatigue, vertigo, colon inflammation, brain fog, and many more.
However, as I only recently learned of my mthfr mutation, I've got some questions.
1) Can I hope to raise my levels to normal through eating lentils every day? I remember reacting very badly to methylB12 in the past and don't wanna try any methyl supplements for the time being. I don't tolerate greens. If so, can I retest my folate levels in a week to see if they start to increase?
2) Does it make sense that eating red meat (high b12 content) several days in a row causes me to be irritable, cranky and anxious? Maybe due to folate/b12 imbalances. I thought it was due to my single iron-overload mutation, but my iron panel is pretty okay at the moment.
3) Does it explain, at least partially, my inability to deal with arsenic and oxalates? Rice and buckwheat tend to make me feel awful if eaten in large enough quantities. I guess a working mthfr cycle is required for both.
severe fatigue, vertigo, colon inflammation, brain fog, and many more.
However, as I only recently learned of my mthfr mutation, I've got some questions.
1) Can I hope to raise my levels to normal through eating lentils every day? I remember reacting very badly to methylB12 in the past and don't wanna try any methyl supplements for the time being. I don't tolerate greens. If so, can I retest my folate levels in a week to see if they start to increase?
2) Does it make sense that eating red meat (high b12 content) several days in a row causes me to be irritable, cranky and anxious? Maybe due to folate/b12 imbalances. I thought it was due to my single iron-overload mutation, but my iron panel is pretty okay at the moment.
3) Does it explain, at least partially, my inability to deal with arsenic and oxalates? Rice and buckwheat tend to make me feel awful if eaten in large enough quantities. I guess a working mthfr cycle is required for both.
