Methylene Blue -- The "Perfect Supplement" For ME/CFS (?)

[Lena9701]

Biocidin is good for me; it's gentle. I started a nattokinase and serrapeptase combo and brought on pretty heavy herx within a week. I always have some binders around (GI detox and MCP) which helped some but not all the way. A few weeks of biocidin brought things under control again.

Then I was able to add the natto/serra slowly back in while keeping on biocidin and gi detox. The whole thing felt positive and I can now take the enzymes with no issues.

 

[Wayne]

Has anyone tried biocidin? It’s an anti biofilm product

I'd never heard of it before, so did an AI query and came up with the following:

Biocidin is a broad-spectrum botanical formula used primarily for supporting gut health, immune function, and addressing biofilm-related issues. It contains a blend of herbal extracts and essential oils, including ingredients like oregano oil and white willow bark.​

 

[Strawberry]

I'd never heard of it before, so did an AI query and came up with the following:

Biocidin is a broad-spectrum botanical formula used primarily for supporting gut health, immune function, and addressing biofilm-related issues. It contains a blend of herbal extracts and essential oils, including ingredients like oregano oil and white willow bark.​

Thats very interesting! My daughter also asked if anyone had tried the anti fungal they use in fish tanks.

 

[mrmichaelfreedmen]

Biocidin is good for me; it's gentle. I started a nattokinase and serrapeptase combo and brought on pretty heavy herx within a week. I always have some binders around (GI detox and MCP) which helped some but not all the way. A few weeks of biocidin brought things under control again.

Then I was able to add the natto/serra slowly back in while keeping on biocidin and gi detox. The whole thing felt positive and I can now take the enzymes with no issues.

Yeah you must have eliminated the biofilm infection with continued use of biocidin, reason why you can now handle the other two systemic enzymes with out a herx.

I agree with Carl, microbes can adapt to ANY anti microbial which has developed a biofilm.

 

[mrmichaelfreedmen]

I have it at home now too. I bought it from https://biolabshop.pl/gb/. They were the only ones I could find that already had it in pill form.
I'm currently testing Oxymatrine and Inosine I don't know if it's a good idea to mix it?

Totally fine to combine inosine with oxymatrine, I did for ages and was the most effective thing I have ever tried following my positive EV biopsy test by Dr Chia

 

[Artemisia]

lol cortisol= lack of AM sunlight, which will rasise it.

what if you have high cortisol? does kruse say AM sun will regulate cortisol either way?

 

[Nord Wolf]

I've listened to a number of articles on MB, and some state that using it to treat ME/CFS it should be taking in conjunction with NAC, LDN, and Red Light Therapy. I have been taking NAC for my lungs for years, and I use redlight therapy daily, but is anyone on LDN because they are taking MB?

 

[Strawberry]

I have been taking NAC for my lungs for years

What does NAC do for your lungs?

I’m on both LDN and MB, although I’ve had to scale back on the MB. I can’t do red light therapy. I’m about to post an update thread.

 

[Nord Wolf]

What does NAC do for your lungs?

I’m on both LDN and MB, although I’ve had to scale back on the MB. I can’t do red light therapy. I’m about to post an update thread.

Hey @Strawberry,

Been a while.

NAC is one of the most potent amino acids for lung support, healing, and function. Even pulmonologists will suggest a person take it if they have lung conditions. About 8 years ago it was suggested I start taking it daily by three of my doctors and pulmonologist. I’m pretty sure most naturopaths recommend it for folks working through pneumonia, covid, and other respiratory illnesses too.

I’ll be interested to hear your MB/LDN update.

 

[Strawberry]

I’ll have to trial NAC again then. Sometimes my lungs sound like a bowl of rice crispies with milk…. Last time I took NAC, it was because someone said it was rocket fuel. It didn’t have that effect on me so I quit. I’m sitting here looking at the bottle with about 20 pills. Wishing it was rocket fuel .

 

[Nord Wolf]

Wishing it was rocket fuel

DITTO! Sadly I've not notice those sort of results from it...
I take between 900 and 1400 mgs daily for my lungs depending on time of year and or how they are feeling. Mine don't have that fluid issue it sounds like yours do. Mine is severe dry inflammation which makes them feel like they are stuffed with dry cotton... making the past time of breathing very difficult. Who knows, maybe I need to find a different past time... Maybe breathing is just overrated.

 

[Nord Wolf]

Update on Methylene Blue –


I have the liquid form where 20 drops equal 10 mgs. I avoided all potential interacting supplements two

weeks prior; L-Dopa, 5-HTP, and L-Tyrosine. I began by taking only 5 drops in the morning on day 1, a very small amount.


By the afternoon of Day 1 I started feeling odd.

• Fragile nervous system
• Frail and shaky
• Increased respiratory fatigue
• Full body weakness and increased overall malaise
• Acute and severe cognitive fog
• Acute upper back, neck and spine pain
• By about 7 pm I was completely exhausted and gutted
• That night I slept horribly and every time I woke up my entire body would start tremoring uncontrollably from severe exhaustion.

The next morning, I took another 5 drops and all the above symptoms continued and worsened.

On the third morning I didn’t take any more Methylene Blue and by the afternoon I was feeling better

and by late morning the following day, day 4, I had returned to baseline.



I waited 8 days and decided to try it again, just to be sure the reaction was in fact from the Methylene

Blue. Again, I began at 5 drops. This time the same symptoms didn’t set in until the second night.

I took 5 drops for 4 days this time, but each day I felt worse and by day 5 I had to stop because those same symptoms were bad enough to show me, they were indeed a reaction from taking the Methylene Blue. I am still trying to return to baseline after the second go-round…



It appears I’m unable to take this “miracle” supplement. I was really hoping, especially from all I listened to on the effects of Methylene Blue, that my body would be able to handle it. However, even at a miniscule dose I experienced acute negative reactions.

I did find this online that I ordered. I’m eager to try it out. Mitochondrial & ATP

 

[Wayne]

I was really hoping, especially from all I listened to on the effects of Methylene Blue, that my body would be able to handle it. However, even at a miniscule dose I experienced acute negative reactions.

Hi @Nord Wolf -- I'm sorry to hear this didn't work for you. I have to say, you gave it much more of a chance to start working after your negative reactions started immediately showing up than I would have. I also have a very sensitive system, which is why I started at 3 drops. I probably should have started even lower, but I did OK with 3 drops.

Interestingly, at one point, after many months, my body seemed to not want it anymore. So I didn't take any for several weeks. When I started it again, I wasn't sure what to expect. What I discovered is that 3 drops is currently the "sweet spot" for me. Who knows how long that will be the case. As with everything we use or try, it's always a continual monitoring process.

I hope you can reach your pre-methylene blue baseline soon!

 

[Mary]

@Nord Wolf - I think 5 drops is a very high dose to start with. I started with one or two drops, I forget which, and felt good but then had to back off because it started to cause insomnia for me. Almost anything that increases my energy causes insomnia for me. So I went down to 1/2 a drop, and then I just stopped it because I didn't want to mess around with any more insomnia.

But one of these days I'm going to try it again, starting with 1/2 a drop and see what happens.

Your symptoms were pretty severe so it's possible that MB is just not for you. But it's also possible you were taking too much.

 

[Nord Wolf]

I'm sorry to hear this didn't work for you. I have to say, you gave it much more of a chance to start working after your negative reactions started immediately showing up than I would have. I also have a very sensitive system, which is why I started at 3 drops. I probably should have started even lower, but I did OK with 3 drops.

Interestingly, at one point, after many months, my body seemed to not want it anymore. So I didn't take any for several weeks. When I started it again, I wasn't sure what to expect. What I discovered is that 3 drops is currently the "sweet spot" for me. Who knows how long that will be the case. As with everything we use or try, it's always a continual monitoring process.

I hope you can reach your pre-methylene blue baseline soon!

I'm still trying to crawl out of the hole the reaction dropped me into. 4 days so far and recovery has been proving very slow. Tis the time of year as well... at least for my system. Weather hasn't been helping either. I was completely blind for the past three days. Today I can see well enough to actually type a small amount using Zoom Tech.

Your symptoms were pretty severe so it's possible that MB is just not for you. But it's also possible you were taking too much.

I agree, when my body reacts so strongly in a negative way to something (considering 20 drops equaling 10 mg is said to be "low dose", and I was only taking 5 drops which is equal to 2.5 mg), then historically it has typically been a sign to avoid. I wasn't really surprised by the reaction as I tend to respond negatively to synthetically derived substances. Haha, I hesitated when I squeezed the drops the color of Easter egg dye into a cup... and chuckled and said nothing like a bit of cobalt in one's diet, right!
But I'm sure MB is great for those who can handle it. There is something out there for all of us. We just have to find it.

 

[Omgitsremy89]

That seems like a pretty adverse reaction that could be die off or potentially something else. Do you have G6PD deficiency? MB is contraindicated in those with that enzyme deficiency.

 

[Nord Wolf]

That seems like a pretty adverse reaction that could be die off or potentially something else. Do you have G6PD deficiency? MB is contraindicated in those with that enzyme deficiency.

Not sure how such a miniscule dose in such a short time could case any die-off. I'm sure it is possible, but with everything else I'm taking, I couldn't imagine what.

I was tested for G6PD prior to taking MB and the results showed normal readings.

But as I stated, my system tends to react harshly to many medications and supplements. I'm sure it is the autoimmune conditions that prompt such hyperreactivity. Though who's to say for sure...

 

[Strawberry]

5 drops is too much for me. My body no longer wants MB.

 

[Nord Wolf]

still in a crashed state from the methylene blue. body just hasn't been able to rebound to its baseline for this time of year. severe pem with intense respiratory inflammation, etc. just laying low.

 

[Wayne]

still in a crashed state from the methylene blue. body just hasn't been able to rebound to its baseline for this time of year. severe pem with intense respiratory inflammation, etc. just laying low.

I'm really sorry to hear that @Nord Wolf.

I'm going to "toss" out something a little out of the ordinary, perhaps something for you to consider. I'm a believer in everything having a vibration. In fact, it's kind of the whole basis of homeopathy. And I can't help but wonder if at least some of what you're dealing with is the vibration of MB still being in your body.

I've had some pretty significant experiences with vibrations, and have figured out various ways to sometimes "nullify" or neutralize them if I feel they're unduly affecting me. If you have any interest, I could share a bit more about this.

I hope you can get yourself back to baseline soon (or better than baseline). All the best navigating your way through this all, and hope you can enjoy the holiday season.