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caledonia I think you mentioned somewhere that you are convinced that low potassium is due to leaky gut ?
No, low electrolytes (sodium, magnesium, potassium etc.) are due to low adrenal function. The adrenals regulate electrolytes and help hold them in the body. When the adrenals aren't working well, the electrolytes will leak out like crazy, and need almost constant replenishment.
Then when you try to restart methylation, your body will start building new cells. Interestingly, this is similar to pregnancy. Both are situations where your body will start demanding more potassium (on top of the potassium you're already losing from weak adrenals). You're "supposed" to be able to get potassium from your diet, and pregnant women are recommended to eat food sources rich in potassium.
I've tried that because my doctor wanted me to, and for whatever reason, it doesn't work for ME patients. You must take a potassium supplement to get adequate potassium. My gut is 100% now, so I don't think it's a gut issue.
At a guess, it's something at the cellular level, unique to ME patients. Yasko mentions balancing potassium, but it doesn't seem to be nearly the issue with autism patients as it is for ME patients. I haven't heard other types of methylation-illness patients complain about this either.
I would also like to mention that I'm one of the ones who doesn't do well with adrenal glandular type supplements. So the only thing I've been able to do for my adrenals is replenish the electrolytes. Now that I'm doing methylation, they need less and less supplementation, which I'm taking as a sign that function is improving. I haven't retested them yet, but they were virtually flatlined for many years - among the four worst my naturopath had ever seen.
RichVank said that this is because the adrenals are malfunctioning due to low glutathione. The glutathione is required to produce signals to make the gland work. The gland itself is fine - it just needs marching orders. So you do methylation, make more glutathione, and the adrenals start working better.
This should improve overall electrolyte status, but I assume you'll still need extra potassium until all the cells get rebuilt.