I would urge you to consider an alternative already suggested to you. The big dose of B12 has increased your need for folate. What you are experiencing is folate deficiency.
A number of people on PR have reported skin breakouts after starting B12 and these responded to folate.
It is easy enough for you to put this to the test. Take a decent dose of methylfolate every few hours and see if the symptoms subside.
You say you are taking folinic. Maybe you are not taking enough or like some people on PR, folinic is not an effective form for you.
Hi
@alicec,
I'm struggling badly at the moment on MB12 injections (1mg/d, but have at least temporarily stopped them). I would love it to be a simple case of either taking the wrong form of folate, or not taking enough potassium, or not enough co-factors, but I've covered all the obvious things (fish oils, extra DHA plus CLO, selenium, zinc + copper, coenzymated B2 and B6, coenz B complex, potassium, vit D3 and K2, Vit A, Vit E, etc) to no avail, and I'm stuck and I would appreciate your advice.
I've also tried TMG (headache, nausea, fatigue), creatine monohydrate (@ a tiny 250mg because I have an issue with chickenpox, shingles, glandular fever, and arginine stimulates the herpes virus in general) and at a 10g (1/2 the recommended loading dose) yesterday, no discernible improvement. Reluctant to increase because of the herpes issue (see my profile info) and anyway think of that as a seperate issue from methylation.
I initially had HUGE improvements using MB12 patches with 1200mcg MB12 + 400mcg plain folic a id, which I wouldn't have thought I'd have been able to convert or use. Found that MTHF 800mcg made me feel very anxious within an hour or so of taking, and this repeats the same experience I had when I switched from folic acid and tried MTHF last year, and the year before that.
Had around 4-6 weeks of being able to get up pretty much every day, drove without wiping myself out, listed vast amounts of items to sell on Preloved, did some cooking - all the normal stuff that I usually can't do. Fantastic.
Had HB12 injections (only two of them, one a day for two days, 1mg again) in late Jan, reacted with my standard toxic response of swollen eyes, lips, nose, nausea and generally feeling poisoned, so switched to MB12 1mg/d.
Didn't give me the same energy burst that I had with the first packet of PurOrganica patches (late Nov thru early Jan). Ordered more patches. Zero good effect from them that time. Continued with the injections. Looked at posts mentioning start-up issues coukd be avoided with bigger 5mg doses. Did one of those, felt better for that day only, still didn't have me up out of bed but felt generally headed in the right direction, woke up next day feeling terrible again. Haven't done it since.
Changed from MTFH to folinic acid, 800mcg. Doesn't seem to cause anxiety like MTHF, but also hasn't apparently improved my overall situation and I'm also getting even more migraines than usual. On the first exposure to MB12 with those patches, I had almost no migraines, no muscle pain, loads of positive changes.
Have tried AdB12 drops, but they seemed to make me immediately worse. Tried low dose of 134mcgs (1 drop = 67mcg), normal-low doses of 1 and 2 mgs, also what seems to be the standard 3mg dose. Produces headache and more fatigue etc. Contains citric acid, and whilst I don't seem to be intolerant of anything that woukd indicate a citric acid sensitivity, it's obv poss that that could the problem there.
Have tried different timings, have tried taking everything together, or all my B12 and folate at same time, after my B6 etc, have tried taking my MB12 and AdB12 seperately from folate (tried before, tried after) or my other supps - I can't hit on the right combo.
Usually, Source Natural's Chem Defense (conenz B2, molybdenum, reduced glutathione) resolves my toxic headaches, but even that doesn't seem to be working for me right now.
Disheartening after being so active in January :-(
Littlebird mentioned L-MTHF - is that still another form of folate, or is it another name for MTHF?
Can usually work out what's going on, but could really use your help as I'm currently just getting myself more and more confused and I don't want to be permanently bed-bound yet again. :-(
Thanks,
Jigsaw