I have been very ill for 4 years, firstly diagnosed with CFS/ME and then in 2015 I tested positive for Lyme Disease. I believe I have a vitamin B12 Deficiency (yet my tests constantly come back sky high) and that I have a blocked methylation pathway. My 23andMe results indicate I need help in this area (Genetic Genie Interpretation attached). I am homozygous for MTHFR C677T / COMT V158M / COMT H62H / VDR Bsm I am heterozygous for MAO-A R297R/ MTR A2756G/ MTRR A66G / CBS C699T. My Mother almost died 20 years ago when they failed to diagnose Pernicious Anaemia, after 9 months deteriation she collapsed and it took 17 days in hospital before they found it. My Father died of Parkinsons. I am now bedridden most days and I'm convinced there is a link here. I do know that with my combination of MTHFR and COMT I need to be very careful with what I take. I'm highly sensitive to most things. I would appreciate any advise. Too ill to work this out on my own. Does anyone know of a specialist who I can consult with via Skype or phone? (I am in the UK ). ANY help at all with this, I'd be most grateful !!