High pregnenolone

nsdn

Senior Member
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Hi guys.

Since taking LDN my hormones are fine but recently I discovered high pregnenolone. Is that good or bad? I can not understand ...

Thanks!

preg.PNG
 
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It could mean that CYP11A1, which converts cholesterol into Pregnenelone is overactive. A full hormone panel might help to tell which steroidogenic pathways are activated and suppressed.

It could also mean Preg isn’t being sulfated into it’s main metabolite Preg Sulfate by sulfation enzymes.