Higher pregnenolone levels may be a sign that your body is having problems converting it into secondary sex hormones (such as testosterone, estrogen, and progesterone). This can cause problems with sexual function or development [
R].
High pregnenolone can be caused by:
- Pain [R]
- Smoking marijuana (THC) [R]
- Congenital adrenal hyperplasia (genetic disorder) [R]
Although there is not much clinical information on the consequences of high pregnenolone levels, people with high pregnenolone levels report experiencing:
- Acne
- Drowsiness
- Anxiety
- Heart problems
Address any existing underlying health issues!
Limit or eliminate marijuana use. THC (the primary active compound in marijuana) can boost pregnenolone synthesis in the brain, which may result in elevated levels [
R].