Has sadly never worked for me. I can no longer bear the financial burden of going through the Merck manual alphabetically. But more importantly I can no longer bear the raising and crushing of false hope. It's just too emotionally painful.
90% of the time they seem like they work for a few days or a few weeks at best and I don't want to risk having a bad reaction to one of the ingredients. I'm too chicken to try anything I haven't ingested previously.
I was saying, "THIS" to the part about trying with a small dose of any of these things first.