As I've been on IFN Lambda I've had reflux issues periodically, and TONS of constant stomach gurgling sounds (which I learned is called borborygmus). You hear this on Lambda because it causes GI tract inflammation, leading to these sounds.Same here. After years spent trying to adjust my diet, I've found things that maybe help a bit. But overall, my triggers seem to be 80% related to exertion (mental or physical) and 20% related to diet. Quite frustrating, because even talking on the phone too much will lead to days of reflux and coughing in addition to the other PEM symptoms. In a current minor crash at the moment - stomach constantly gurgling like it's trying to digest, slight burn causing coughing and discomfort, etc. Not pleasant.
So there could be a connection between exertion, which lowers intracellular immunity leading to increased viral replication, and the stomach/GI tract inflammation and reflux.