Sounds like some severe vasoconstriction - caused by high lysine/not enough arginine intake?
Hey
@Gondwanaland thank you so much!!! your post changed my life to the better. Instead of arginine, I had a box of citrulline at home. This is largely the same in the urea cycle as arginine and converts into NO (nitric oxide) thus improves blood flow.
Effect 1:
within 1-2h, this painful feeling that my leg sleeps away diminished to a level that I could sleep. Happy as a bird!! And very interesting, as I did not seem to have hypoperfusion: no cold limb.
Effect 2:
Less time in bed because of my POTS!! It has a nice effect on digestion speeding it up a lot.
Side effect:
I needed to go far over the recommended dosage, because the badly needed Effect 1 lasts only a few hours. After taking citrulline for two days, I got aggressive thoughts, pumped up mucles and a high desire to drink water with vinegar. These all fit high ammonia.
Vinegar neutralises ammonia. Since then, I am drinking cups and cups of water with vinegar all the day.
Interpretation?
All this painful leg sleeps away problem came upon me after I happily supplemented increasing mini-doses of B1 and then ate 1 can of mackerel. Looking back, my previous two sudden worsenings of neuropathy also came after exactly this combo. Mast cells are triggered by thiamine and by not fresh fish.....
Maybe the leg sleeping away is not the real problem, but a useful feeling my body produces to trigger me to do things improving blood flow, to help neurons survive? After suffering the damage,, I immediately started massaging the leg, do sports, put hot water bottles and warm cloth on it ... then accidentally found that trick with the breathholding (which increases CO2, which is a strong vasodilator). The citrulline / NO could increase blood flow beyond normal? or improve microcirculation? The need for the bigger blood flow could be to enable repair of neurons?
I already had an unopened box of citrulline at home, bought a year ago for some unconcrete plans to experiment with tweaking NO production . It was clear to me that I have a problem: A previous experiment using a tiny 2mm morsel of Corvatone (Molsidominum, a NO donor) led to such an overwhelming effect that I prayed to all gods that it stops...
I still wonder how all this works, but it is wonderful! Thanks
@Gondwanaland !!It seems like this time I escaped permanent neuronal damage. This was the best treatment suggestion I received in a long time!! Happy!!!
My lysine and arginine intakes during the days before the catastrophy happened:
09.06.2017 Arg: 2g, Lys 2.8g
08.06.2017 Arg: 2.8g, Lys: 3.5g
07.06.2017 Arg: 2.3g, Lys: 3g
06.06.2017 Arg: 2.5g, Lys: 3.2g
These correspond to my typical intakes.