• Welcome to Phoenix Rising!

    Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of and finding treatments for complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia (FM), long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.

    To register, simply click the Register button at the top right.

Found good integrative doctor: need input on OAT, TOX and DNA testing

HABS93

Senior Member
Messages
481
As much as I love my MD he's not guna be able to help me. It's hard to post on here as work is kicking me butt. He ordered a OAT + toxicologist test and a DNA genetics. He actually saved me alot of money on these test. Has anyone got these test at all?
 

HABS93

Senior Member
Messages
481
Hi @HABS93 , and as always, it's good to see you posting :):) :hug::hug:.

You might want to re-title your thread with something like NEED GENERAL INPUT ON OAT, TOX, AND DNA TESTS, which is more likely to draw the specific kind of info you need, rather than the general, sort of chatty title you've currently got.

Not than you asked me, but ....
I apologize really bad brain fog getting use to work again. Alot has happened yet feel dead.
 

HABS93

Senior Member
Messages
481
I honestly feel stuppid but I can't find hope to edit this post so I'll start here.
My diet is finally what I want. I'm eating chicken breast and 9cups of veggies everyday with fish 3x a week. Drinking cocunut water . Using a MCT protien shakes as well as a veggie smoothie in the morning with breakfast.
My integrative doctor got toxicology OAT and a DNA genetics test I'm going to upload them if anyone can help me go through them more .
I'm on orthho multi men twice a day, NAC X3 , vit D3&K2 , probiotics 50 strains once a day. I've been ppowering through the random nauseousness I get from them. This stopped when ii stopped taking the omega 3 finish oil supplements. Probably because I eat eggs everyday don't need the supplement.
I feel brain dead lately. Weird shakiness sometimes. Hoping it's just a detox reaction but it's been three weeks now.
 

Attachments

  • JAKE_CARROLL_TOX V2_ENG.PDF
    231 KB · Views: 17
  • JAKE CARROLL DNA RESULTS.PDF
    3.5 MB · Views: 12

YippeeKi YOW !!

Senior Member
Messages
16,013
Location
Second star to the right ...
@HABS93
I'm dealing with some symptomatic flare stuff right now, so not able to dig really deep into your DNA test yet, but a couple of things caught my attention ....


B-VITS .... You're at risk for reduced MTHFR activity, and are directed towards avoiding FOLIC ACID, and instead taking the more active form, 5-Methylfolate or L-5-MTHFR, which helps you convert homosysteine to methionine, detoxify, and improves production of serotonin.

They also recommend supplementing with hydoxycobalamin for B-12 needs, which will be less over-stimulating to your particular system.

The above are methylation issues, and if you address them, it can make a world of difference.

Regarding OMEGA 3 FATTY ACIDS, you need a pretty good amount of them ... you have variants in at least one of the genes known to impact the need for omega 3 fatty acids, putting you at risk for certain diseases, includinh metabolic syndrome, which can be a precursor to everything from diabetes to cardio issues (tho not specifically mentioned) if you dont get enough omega 3's.

Eggs are not a good source of omega-3, unless you're buying specially produced hi Omega-3 eggs. Fish and fish oil are the best sources.

On Pg 16, relating to IRON, your ability to transport iron to your tissues may be reduced, which might explain your exhaustion and brain deadery, and could lead to iron-deficiency anemia. It suggests supplementing with 15 mcg a day, with Vit C to assist in absorption .... I'd copy and paste the exact quote, but it's encrypted, so it would make zero sense. You have the typical or normal version of the HFE gene, which protects against hemochromatosis, so you likely have normal levels of transferrin, which limits the amount of free iron in your body to safe levels.

The Weasel Words of 'likely', 'may', 'possibly' appear frequently thru-out the report, but those aside, it seems to be pretty thorough.

On PROBIOTICS, the test results show that you have a gene variant that may negatively affect the levels of your gut microflora.

They recommend supplementng with the primary beneficial bacteria, bifidobacterium, along with 2'-fucosyllactose, a beneficial prebiotic that will feed and support the equally beneficial bifido.

I think that a lot of us have been mislead into believing that probiotics are a harmless, highly beneficial, sort of scattershot thing we can do for our gut, whereas it can actually cause a lot, and I mean a whole lot, of discmfort and difficulty.

If you start introducing dozens and dozens of foreign strains of bacteria into your intestines, you can trigger a ground war between your basic bacteria, your commensal bacteria, and the invading foreign strains. It's usually safer to take a decent prebiotic, which will feed the bacteria already present, with different kinds of prebiotic bacterial food encouraging the solid establishment of different kinds of beneficial bacteria, rather than throwing a lot of stuff into the pot and letting them sort it out themselves, which rarely ends well.

I'm guessng that this might be the source of your bouts of nausea ....

I'm cross-eyed with fatigue and some familiar, recurring pains, I have to stop now. I'll be back, probalby tomorrow, to continue this, if you think it's helpful. Please let me know ...

You're doing a whole lot of things RIGHT, HABS .... just hang in while the rough spots and wrinkly areas are ironed out, and things should get better pretty fast.

Sending hug :hug: .... one is all I can manage right now ... really really tired ....
 

HABS93

Senior Member
Messages
481
Man I wish I could help you. This is great. Better then me trying to Google search everything on list and not finding everything. I hope you're doing better. I leave my trust in God.
So the B vits is enough to take with the ortho multi men I take twice a day? This gets so confusing. All of this information is extremely helpful for me.
I just started taking the probiotics yesterday and it made me feel brain dead so I'm guna take it at night before bed. My integrative doctor said to take the 50 strains ones but your detailed response making me think otherwise .
My mom has a iron deficiency but why does my levels come up normal in my blood ? My symptom's two years ago I thought was anemia . So what do you mean as a resolution for this ?
I'm taking a good amount of vit C .
The toxicology is kind of scary to look at. I wonder if the NAC is starting my detox along with all the veggies and chicken/salmon I'm eating. I'm also eating a while fibre cereal with hemp seeds mixed in it. The multi vitamin has all my B vitamins as well.
 

YippeeKi YOW !!

Senior Member
Messages
16,013
Location
Second star to the right ...
The multi vitamin has all my B vitamins as well.
Depends of what forms of each B-vit they use. A lot of multi's, especially the very reasonably priced ones, use the cheapest, most inert forms, like Folic Acid Vs. 5-Methylfolate or L-5-MTHFR or even simple folate, tho because of your potential MTHFR difficulties, you might want to stick to the L-5-MTHFR.

You'll need to take a look a the sources of your vitamins in your multi, or post a brand name that can be searched out and checked on the internet.

Isn't your Dr going over any of this with you? It's an awful large load to dump on you when you're struggling to stay afloat ....
 

HABS93

Senior Member
Messages
481
@YippeeKi YOW !! Oh okay I under more now. He's gone over some of the test and increased my NAC amount . The multi is protocol for life balance. It's shows folic acid in this multi.
I know it's alot and I'm trying to understand it as best of my abilities. What do I do about the iron? I know things still suck but I feel I'm alot closer to figuring out what's going.
 

HABS93

Senior Member
Messages
481
@YippeeKi YOW !! Adding on could it be that I read definition of what this means "Any defect in the MTHFR enzyme may cause under methylation. This under methylation can lead to insufficient folate conversion which can further cause limited methyl groups conversion, thus resulting in accumulation of toxic elements such as heavy metals and other chemicals" So if I didn't have this problem my body could of gotten rid of the metals ? Could this be possibly what's going on?
 

YippeeKi YOW !!

Senior Member
Messages
16,013
Location
Second star to the right ...
It's shows folic acid in this multi.
Hiya HABS ...
FOLIC ACID is the cheapest, least effective form of folate, and if you have MTHFR issues, which you apparently do tho to what degree I cant figure out, none the less, your DNA profile recommends the L-5 MTHFR form for full absorption ....


Lemme guess. Did your Dr sell you the multi you're taking? Or recommend it? How did you happen to settle o this particular brand?
 

HABS93

Senior Member
Messages
481
Does this count as a methylation mutation ? Reading into this seems fragile if there's anything wrong with your methylation cycle. Oh of course its his . To be fair he recommended these supplements before the test. We just went over it Tuesday. Not all of it didn't have enough time.
That was the brand name on the supplement. Then just says Ortho multi men . Strange it doesn't have any iron in it ha. That's okay I feel the same way. I'm also absorbing small amounts of packets.
 

YippeeKi YOW !!

Senior Member
Messages
16,013
Location
Second star to the right ...
@YippeeKi YOW !! Adding on could it be that I read definition of what this means "Any defect in the MTHFR enzyme may cause under methylation. This under methylation can lead to insufficient folate conversion which can further cause limited methyl groups conversion, thus resulting in accumulation of toxic elements such as heavy metals and other chemicals" So if I didn't have this problem my body could of gotten rid of the metals ? Could this be possibly what's going on?
Here's what I wrote to you, above:
B-VITS .... You're at risk for reduced MTHFR activity, and are directed towards avoiding FOLIC ACID, and instead taking the more active form, 5-Methylfolate or L-5-MTHFR, which helps you convert homosysteine to methionine, detoxify, and improves production of serotonin.

They also recommend supplementing with hydoxycobalamin for B-12 needs, which will be less over-stimulating to your particular system.

The above are methylation issues, and if you address them, it can make a world of difference.
So yes, you're apparently a slow methylator, as well as I can tell from your DNA profiling, and any help you can give to that process could help you detox isues.


Keep in mind that I'm not a medical practitioner of any kind, and all I can do is share what I've learned, usually the hard way, and hope that it helps. I know what it feels like to be lost in a sea of information that I can;t quite grasp but know that I desperately need to, so anything I can do to help you, I will.
 

YippeeKi YOW !!

Senior Member
Messages
16,013
Location
Second star to the right ...
Strange it doesn't have any iron in it ha.
A lot of vitamins dont, and that's a good thing. Iron can build up in your body and cause problems like hemochromatosis. But your DNA profile clearly states that you have normal genetics re: clearing iron from your system, so if you supplement 2 or 3 times a week, always with Vit C and maybe just before bed, you should be OK.


One of the gentlest forms with the lowest side effect profile is Iron Bis-Glycinate. I use Solgar's because, as I've said regarding the magnesium I take, I trust the company and they make quality products.
That's okay I feel the same way. I'm also absorbing small amounts of packets.
We're perfectly matched then :hug::hug: :xeyes::xeyes::xeyes: .....
 

HABS93

Senior Member
Messages
481
@YippeeKi YOW !! Yeah before bed is easier beacsue any weird reactions you can by pass by sleeping. I usually just take multi and NAC before work and that's it. I'll get some bis-glycinate from solgars.
It feels like a maze that's impossible to get out of. It's sad I don't even remember what I use to feel like when I was normal.
 

YippeeKi YOW !!

Senior Member
Messages
16,013
Location
Second star to the right ...
It's sad I don't even remember what I use to feel like when I was normal.
I know the feeling. I find that focusing on the job of getting better, and knowing that its possible, keeps my head above water.


When I feel negative thoughts like that coming on, I thank them for sharing and politely tell them to eff off ... it works most of the time, when it doesn't I have a little pity-party wallow, and then I struggle back to more positive ground.
 

YippeeKi YOW !!

Senior Member
Messages
16,013
Location
Second star to the right ...
@YippeeKi YOW !! What are your thoughts on getting one of those infa red saunas to help your detox system ?
I think that red and near-infra red light therapy can work wonders, tho I'm not as conversant with infra -red saunas. I've been slowly looking into NIR and Red light therapy in my slow plodding way ....

Here's a thread on near-infra red light therapy that might help .... there are a lot of posters who seem to have solid deep knowledge that you could question about this ....

Red And Near Infra-Red Light Therapy
https://forums.phoenixrising.me/thr...-light-therapy-leds.79181/page-4#post-2289610

I'm crashing and am going to have to take a break, Will be back later with more back and forth about your tests and anything else that interests you, yes :hug::hug::hug: ???
 

HABS93

Senior Member
Messages
481
@YippeeKi YOW !! My doctor suggested to do it once aa week and brush my skin before I do it. Good things I've read from the link you posted . I can see it helping. Hope you feel better. The toxicology test confuses me more then the DNA one. Thank you for taking the time when you can though. I appreciate it alot. I gotta go to work but it's my last shift of the week. I got questions just hard to. Word them right. It's like my brain has trouble spitting them out.