For Arbidol (umifenovir) I was not able to calculate the Potency Factor, for a number of reasons (one of which is that Arbidol may have immunomodulatory effects as well as antiviral actions in fighting viruses, and accounting for the former is beyond the scope of my calculations; I can only calculate the antiviral action).
Arbidol might be useful for coxsackievirus B ME/CFS, as there are a couple of in vivo mouse studies that showed this drug has a substantial antiviral effects against acute CVB infection:
But as you can see from these studies, the equivalent human dose is quite high, around 300 to 600 mg. It would be a little bit expensive to take 600 mg of Arbidol daily. I actually tried taking 100 mg daily for around 5 weeks, but did not notice any improvements in ME/CFS symptoms (I have an active CVB4 infection). But this was a low dose.
's wife who has ME/CFS tried Arbidol 400 mg daily (see this post
), and observed some improvements. I am not sure of the long-term outcome, as he stopped posting.
Arbidol is a well-tolerated drug, and I have seen studies where doses of 800 mg daily were used.
So it might be worth trying Arbidol as an experiment. At rupharma.com
, Arbidol costs 1 euro for each 100 mg tablet. Arbidol can also be bought here