ChookityPop
Senior Member
- Messages
- 605
I have now tested positive for CN-1a which is mainly seen in Inclusion body myositis (IBM) patients over the age of 50 but also in other autoimmune diseases like LUPUS, Sjogrens and more. Due to the age of IBM onset this antibody is likely to be tested less frequently in younger patients.
I have now found quite a few ME/CFS patients with this antibody and they don't seem to have the typical IBM symptoms. For example I have full body muscle weakness which is not def not common in IBM at least not my level of weakness. But I have also found a case study of an IBM patient with only weakness of the calf and thighs so there seems to be a wide range of presentation and perhaps different subsets that the litterature havent caught up to yet. https://academic.oup.com/labmed/article/41/7/393/2657555
There also seem to be quite a number of vax injured people positive for this antibody with muscle weakness.
This makes me think there is a subset of ME/CFS, LC and vaccine injured that are positive for this antibody and it likely contributes to their ailments. I would love to see the frequency of this antibody in ME/CFS, LC and vaccine injured.
There are ongoing trials with ABC008 which shows promise in stopping progression in muscle weakness. https://abcuro.com/uncategorized/ab...for-the-treatment-of-inclusion-body-myositis/
EDIT: Let me add that my disease is VERY different to the standard IBM patient. Whats interesting is that if they exert over their limit they often get permanent worsening.
I tested cN1A (Mup44), IgG at Synlab in Germany. Its a low cost antibody test for around 30 euros
I have now found quite a few ME/CFS patients with this antibody and they don't seem to have the typical IBM symptoms. For example I have full body muscle weakness which is not def not common in IBM at least not my level of weakness. But I have also found a case study of an IBM patient with only weakness of the calf and thighs so there seems to be a wide range of presentation and perhaps different subsets that the litterature havent caught up to yet. https://academic.oup.com/labmed/article/41/7/393/2657555
There also seem to be quite a number of vax injured people positive for this antibody with muscle weakness.
This makes me think there is a subset of ME/CFS, LC and vaccine injured that are positive for this antibody and it likely contributes to their ailments. I would love to see the frequency of this antibody in ME/CFS, LC and vaccine injured.
There are ongoing trials with ABC008 which shows promise in stopping progression in muscle weakness. https://abcuro.com/uncategorized/ab...for-the-treatment-of-inclusion-body-myositis/
EDIT: Let me add that my disease is VERY different to the standard IBM patient. Whats interesting is that if they exert over their limit they often get permanent worsening.
Last edited: