- Messages
- 13
- Likes
- 15
Hi,
I posted this in my welcome thread but thought I would get more success posting here as this seems more tailored to what I would like to discuss:
I was 'floxed' in 2015 and left with the following symptoms:
Stuck in fight or flight stress response state (worst symptom) which takes my overall energy and concentration.
Peripheral neuropathy which is aggravated by consumption of glutamate in food or stress.
Severe visual snow and palinopsia with floaters.
Brain fog, head pressure esp after eating.
Impaired ability to think and forming sentences
Joint pain muscle weakness
Many food sensitivities - mainly sulphur/glutamate/carbs/sugars (I have aspergillus in gut as per OAT and CBS SNP and suspect Mercury tox)
Stomach ulcer/gastritis - Cant get off PPIS' Cant take supplements to get rid of aspergillus as they aggrave ulcer, vicious circle.
Super hypersensitive to supplements/medication
MCS
Fatigue and general malaise
Depression
I am about 6 years out from the adverse event. For around 2 of those years I was pretty much disabled but unsure of how to address. The facebook groups did not really appreciate how to address the problem other than "be healthy" whatever that means. I carried out stool testing which was inconclusive at the time as I thought it may be gut related. I was then lead to the possibility of heavy metal toxicity years later through a naturopath. The thinking is that the recent EMA findings on one of the mechanism of action of FQ antibiotics is that they are able to chelate minerals from the body. Perhaps I had a body burden of mercury and the FQ redistributed it to critical parts of the body. My reaction was immediate within 30 minutes and it felt like a bomb had gone off in my body. I was crippled, but while the neurological symptoms were immediate, the physical symptoms manifested later.
I then underwent a hair test and it revealed I am very low in the full panel of minerals that the Yasko hair test evaluates. I took this information to the Andy Cutler support group and they claim I meet 3 counting rules for mercury and am mercury toxic. I thought this correlated with my inability to tolerate sulphur in any form (food or supplement). I began DMPS chelation and completed approx 20 rounds but it was very hard going and the dose never exceeded 1mg. My symptoms improved slightly but I dont know if I can attribute this to the chelation of the simple passage of time.
Fast forward a few more years I learn of genetic testing/methylation and SNPs though this channel. I order a 23andme test to see which SNPs I have. Here is the list for the methylation panel:
COMT V158Mrs4680GG-/-
COMT H62Hrs4633CC-/-
COMT P199Prs769224GG-/-
VDR Bsmrs1544410TT+/+
VDR Taqrs731236GG-/-
MTHFR C677Trs1801133AA+/+
MTHFR A1298Crs1801131TT-/-
MTR A2756Grs1805087AG+/-
MTRR A66Grs1801394GG+/+
MTRR K350Ars162036AA-/-
MTRR R415Trs2287780CC-/-
BHMT-02rs567754CT+/-
CBS C699Trs234706AG+/-
SHMT1 C1420Trs1979277AG+/-
I therefore attempted to take low dose 5-mthf (literally a toothpick dose of 400mcg) in order to address MTHFR C677T+/+ SNP but was unable to tolerate and this sent me into an anxious overdriven nightmare of which I have not fully recovered. Reading the many posts on this forum I learned that according to Yasko one must address the gut and CBS first. Since my gut problem is difficult to address due to the ulcerations i began work on CBS. I bought the supplements and began moly. I began to feel worse but again its so difficult to assign causality here as I generally wax and wane in symptoms.
I bought the urine sulphate strips and to my surprise urine sulphate was between the 200 - 400 range. This would go against the logic on the heartfixer site for this SNP and im now totally confused on how to proceed. I seem to tolerate protein well but its carbs and vegetables that give me issues.
My goal is to support methylation then begin ACC chelation once again so I can use higher doses.
Thanks for reading, I hope that someone can point me in the right direction on where to go from here.
I posted this in my welcome thread but thought I would get more success posting here as this seems more tailored to what I would like to discuss:
I was 'floxed' in 2015 and left with the following symptoms:
Stuck in fight or flight stress response state (worst symptom) which takes my overall energy and concentration.
Peripheral neuropathy which is aggravated by consumption of glutamate in food or stress.
Severe visual snow and palinopsia with floaters.
Brain fog, head pressure esp after eating.
Impaired ability to think and forming sentences
Joint pain muscle weakness
Many food sensitivities - mainly sulphur/glutamate/carbs/sugars (I have aspergillus in gut as per OAT and CBS SNP and suspect Mercury tox)
Stomach ulcer/gastritis - Cant get off PPIS' Cant take supplements to get rid of aspergillus as they aggrave ulcer, vicious circle.
Super hypersensitive to supplements/medication
MCS
Fatigue and general malaise
Depression
I am about 6 years out from the adverse event. For around 2 of those years I was pretty much disabled but unsure of how to address. The facebook groups did not really appreciate how to address the problem other than "be healthy" whatever that means. I carried out stool testing which was inconclusive at the time as I thought it may be gut related. I was then lead to the possibility of heavy metal toxicity years later through a naturopath. The thinking is that the recent EMA findings on one of the mechanism of action of FQ antibiotics is that they are able to chelate minerals from the body. Perhaps I had a body burden of mercury and the FQ redistributed it to critical parts of the body. My reaction was immediate within 30 minutes and it felt like a bomb had gone off in my body. I was crippled, but while the neurological symptoms were immediate, the physical symptoms manifested later.
I then underwent a hair test and it revealed I am very low in the full panel of minerals that the Yasko hair test evaluates. I took this information to the Andy Cutler support group and they claim I meet 3 counting rules for mercury and am mercury toxic. I thought this correlated with my inability to tolerate sulphur in any form (food or supplement). I began DMPS chelation and completed approx 20 rounds but it was very hard going and the dose never exceeded 1mg. My symptoms improved slightly but I dont know if I can attribute this to the chelation of the simple passage of time.
Fast forward a few more years I learn of genetic testing/methylation and SNPs though this channel. I order a 23andme test to see which SNPs I have. Here is the list for the methylation panel:
COMT V158Mrs4680GG-/-
COMT H62Hrs4633CC-/-
COMT P199Prs769224GG-/-
VDR Bsmrs1544410TT+/+
VDR Taqrs731236GG-/-
MTHFR C677Trs1801133AA+/+
MTHFR A1298Crs1801131TT-/-
MTR A2756Grs1805087AG+/-
MTRR A66Grs1801394GG+/+
MTRR K350Ars162036AA-/-
MTRR R415Trs2287780CC-/-
BHMT-02rs567754CT+/-
CBS C699Trs234706AG+/-
SHMT1 C1420Trs1979277AG+/-
I therefore attempted to take low dose 5-mthf (literally a toothpick dose of 400mcg) in order to address MTHFR C677T+/+ SNP but was unable to tolerate and this sent me into an anxious overdriven nightmare of which I have not fully recovered. Reading the many posts on this forum I learned that according to Yasko one must address the gut and CBS first. Since my gut problem is difficult to address due to the ulcerations i began work on CBS. I bought the supplements and began moly. I began to feel worse but again its so difficult to assign causality here as I generally wax and wane in symptoms.
I bought the urine sulphate strips and to my surprise urine sulphate was between the 200 - 400 range. This would go against the logic on the heartfixer site for this SNP and im now totally confused on how to proceed. I seem to tolerate protein well but its carbs and vegetables that give me issues.
My goal is to support methylation then begin ACC chelation once again so I can use higher doses.
Thanks for reading, I hope that someone can point me in the right direction on where to go from here.