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Can someone link me or tell me if there is a good place that had a good method to control a CBS mutation. Thank you!
Can someone link me or tell me if there is a good place that had a good method to control a CBS mutation. Thank you!
Thanks for the info Ahmo.Patrick's links are what I would have posted. You might also try mthfrsupport.com, where there are some good tips.
Just a note about using things to balance out ammonia, one of our concerns. I started with yucca, recommended by Yasko. I used tincture since I didn't want the starch. But it tastes awful. Then someone mentioned ornithine, a tasteless amino acid. It's replaced yucca for me. Also butyrate, mentioned by someone in PR. Sterling Hill of mthfrsupport was where I learned about using lysine to help detox sulfur. I use it both in footbaths and orally.
Re food, I've eliminated all thiols from my diet, but still include small amounts of meat. A good place to learn about this, and a different viewpoint from Yasko/Heartfixer is from Andy Cutler:
http://livingnetwork.co.za/chelationnetwork/food/high-sulfur-sulphur-food-list/
Also, here's a long and extremely useful thread re sulfur:
http://www.mothering.com/community/t/1053485/sulfur-sensitivity
cheers, ahmo
Just a note about using things to balance out ammonia, one of our concerns. I started with yucca, recommended by Yasko. I used tincture since I didn't want the starch. But it tastes awful. Then someone mentioned ornithine, a tasteless amino acid. It's replaced yucca for me. Also butyrate, mentioned by someone in PR.
Thanks for the info Ahmo.
That second link has some contradictory information in it about sulfates. Sulfates are the end product of the trans-sulfuration pathway. The process of sulfation in the liver is part of detoxification. But raising sulfates will NOT help with the cbs related flux nor lower sulfites.
Did you stop taking yucca only because of the taste? Did it work for you?
Which butyrate do you take? (I found this one, but haven't bought it yet) Are there any side effects?
Thanks
Was the manganese advisory because of antagonism to iron absorption? Just curious.Thanks for clarifying this. This link was in my early efforts to understand sulfur. I still wouldn't be able to find the mis-info you caught.
Also, re lysine balance, that's really interesting that there's a connection. I'm also taking manganese, away from my other minerals as I've heard either Dr. Klinghardt or Kamsteed has advised. ahmo
Was the manganese advisory because of antagonism to iron absorption? Just curious.
AVS, the references I've seen for sulfate testing suggest testing weekly. My understanding is that the need for us to correct the methylation cycle is of the highest priority. I'm taking a lot of supplements, including B vits. These all contribute to the sulfur/thiol burden. But I've eliminated all foods of this category, with the exception, by some definitions, of small amounts of meat. I've tested consistently >400. My testing was only after 4-5 months without hi thiol foods. I've been slowly implementing Freddd's protocol. Each of the elements of the "Deadlock Quartet" has been critical for me, both in improving daily experience, and in over-dosing with subsequent symptoms. Freddd may well be at some core truth in his belief that the B12/folate dysfunction may well be at the heart of many of our illnesses.I've just started taking yucca, molybdenum, Yaskos CBS/NOS support, and charcoal (at nights on occation) and I haven't noticed any difference yet. My urine sufate strips test about 800 for the first morning urine and then it drops from about 200-400 in the after noon and night. Does anyone know what time we should be testing our urine sulfate and or have suggestions on supplementatio? Also, I am +/+ for MTHFR 677 and was wondering if I should be taking methylmate B (or any other active folate) while I am trying to get my sulfates down?
Thanks
The CBS homozygote you list in you signature is the A360A +/+. That is not the C699T mutation that is correlated with increased trans-sulfuration flux (which is only a 10-15% bump anyways, the 10x upregulation is a faulty meme perpetuated by the Yasko followers that is simply wrong). Dr Yasko is to my knowledge the only one that sees A360A relevance to clinical observations and I am pretty sure she considers A360A to be the much less severe of the two. If I am wrong in that regard then she and her camp are about the only ones on the planet who do.Thank you everyone for the input, I really appreciate it. I feel okay, I do feel " foggy" and forgetful some days but I can't pinpoint any one cause. I am mthfr 677 ++ and SHMT +/- and I've noticed that I get more foggy when taking SHMT spray and methyl mate B. I am also starting to think that molybdenum gives me a headache. I don't mind these symptoms if they are detox but my concern is that I may be spinning certain wheels while others are stuck and am feeling adverse affects because I haven't totally treated the CBS a d I am losing everything down the transulfuration pathway. Any thought on that?
Thanks