Paleo/Keto is among the most nutrient dense diets that you can get.
Paleo and keto are 2 different diets. They can overlap, but much of the time, they don't.
I would agree that Paleo diets are more nutrient dense than most other diets. However, they are low in calcium and can be very high in oxalates, a toxin that can doba lot of harm.
Keto diets are low in both carbohydrates and protein. The ME/CFS researchers have found that we tend to be short in amino acids, so this could be a bad idea. And for those of us who have trouble with fatty acid oxidation, as
@gbells mentions, we need need carbohydrates.
It is also settled evolutionary science and paleontology that we humans, during our entire evolution of hundreds of thousands of years, did not eat a lot of meat until very recently. We are not evolved to eat paleo, keto, or carnivore long term and they are damaging.
Er, traditionally Inuit cuisine (or Eskimo cuisine), which
includes Greenlandic cuisine and Yup'ik cuisine, consisted of a diet of animal source foods that were fished, hunted, and gathered locally
The bulk of the diet consisted of:
Sea mammals such as walrus, seal, and whale. Whale meat generally comes from the narwhal, beluga whale and the bowhead whale. Ringed seal and bearded seal are the most important aspect of an Inuit diet and is often the largest part of an Inuit hunter's diet. Land mammals such as caribou, polar bear, and muskox Birds and their eggs. Saltwater and freshwater fish including sculpin, Arctic cod, Arctic char, capelin and lake trout.
They were not able to cultivate any vegetables, but did occasionally supplement the foods above with roots, tubers, and berries that they were able to gather from the wild, when they were not covered with snow.
For hundreds of thousands of years most days we only ate vegetables and fruits and meat was an infrequent privilege. In fact, if you look at almost every single indigenous culture still existing today that follows the same diet that they’ve followed for thousands of years, they all eat only small amounts of meat and tons of vegetables and fruits.
As pointed out above, this is absolutely untrue. There are a wide variety of diets eaten by indigenous peoples, from mostly carnivore to mostly vegetarian, depending upon foods available in the local area. The one thing they all had in common was being omnivore to some degree.
Plant based antioxidants are only required to handle damage created by plants. There is no scientific proof whatsoever that a carnivore diet causes DNA damage. In fact, science says just the contrary:
There are no studies long-term on a carnivore diet.
We could debate this particular topic for a very long time. I will just give you one example, and that's resveratrol.
"As a natural food ingredient, numerous studies have demonstrated that resveratrol possesses a very high antioxidant potential. Resveratrol also exhibit antitumor activity, and is considered a potential candidate for prevention and treatment of several types of cancer. Indeed, resveratrol anticancer properties have been confirmed by many in vitro and in vivo studies, which shows that resveratrol is able to inhibit all carcinogenesis stages (e.g., initiation, promotion and progression). Even more, other bioactive effects, namely as anti-inflammatory, anticarcinogenic, cardioprotective, vasorelaxant, phytoestrogenic and neuroprotective have also been reported."
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164842/#:~:text=As a natural food ingredient,of several types of cancer.
If there is a diet that shows only positive health markers and is in line with our human evolution and how our bodies are built the diet people should follow is intermittent fasting. There isn’t one sound research paper showing anything negative about this diet.
There aren't any long-term studies on people with intermittent fasting either. It currently seems to be a good idea, but most of the studies are on much shorter lived animals. Again, sick people like us may have different needs than the diet being currently pushed by the longevity folks. I interviewed a doctor who's pushing people onto Walter Longo's fasting mimicking diet, shared my labs, And what my doctors and I have found about my health and tendencies, and he very quickly decided it was a very bad diet for me, even though it could be a helpful diet to most obese Americans on a standard American diet. As I'm neither and have ME/CFS and the labs that I do, it is not appropriate for me.
There is no substitute for testing to see what one's nutrient status is and one's tendencies, And then one can choose a diet. But, unfortunately most dietary research is either done on animals with a controlled diet, and there are a lot of reasons why what animals are fed is not right for people, or they are observational studies at best, and done for a short periods of time, and not for a lifetime to make be able to make any good conclusions. We are all genetically different and have different environmental factors and especially microbiomes, so that the same diet is not right for all of us.
D-ribose and nicotinamide riboside which are energy work arounds with a reduced fat diet are what you want to boost energy.
Not everyone can use nicotinamide riboside. It has to go through more conversion to get to NAD+ then simply taking NAD+ or the substance that's only one step away, NMN. I have tried two two month trials of high dose NR, which had absolutely no effect on me, after much hype by the people pushing it. It was a complete waste of money. I do well with low dose NMN or NAD+, and NADH works well, too, it's just a lot more expensive to get. There are multiple threads discussing it, so you may want to post about this there and not derail this thread.
