I experimented to the Nth degree with vitamin B12 and the methylation protocol. I have tried various forms of B12: methylcobalamin, adenosylcobalamin and hydroxocobalamin, using Freddd-recommended brands. I have tried many ways of ingestion, including injectables (of hydroxocobalamin), rectal infusion (which I think is the most effective after injection), intranasal, and upper lip mucous membrane administration. I have tried folinic acid and L-5-MTHF.
I have also tried taking all the co-factors suggested by Freddd (like carnitine fulminate, alpha lipoic acid, TMG) which he says might potentially block the effects or benefits of B12, but these did not help.
My MTHFR C677T is +/+ (homozygous) and my MTHFR A1298C is -/- (no mutations).
That is very interesting.
I think there may be two (possibility related) phenomena here: the sensitivity and mental tension that arises from the immediate presence of people; and the way the "feel" of certain experiences can inappropriately intrude into the mind.
I myself don't have any problems with places and locations, but I certainly find that the "essence" and "energy" of people, if I spend several hours in their company, will intrude into my mind, so that I feel as if I have been in some way poisoned or contaminated by them. It then takes me a day or two of solitary activities to come back to myself, and clean my mind of these extraneous essences and opinions of other people.
It is as if talking with people for several hours kind of puts things out of place in my own mind, and I then need solitary time to reorder myself.
This phenomenon occurs even with very good friends, and as a result it means that I tend to limit my social activities to one or two social sessions a week (by social sessions I mean say a quiet evening out with friends, or visiting a friend in their home). I find I need a day or two to mentally recover and "decontaminate" my mind after such sessions.
These social sessions also exhaust me mentally, and the exhaustion seems to go hand in hand with this feeling of the "energies" of people getting too deep into my mind and soul. My ME/CFS is primarily mental, not physical. I can run a mile relatively easily, but get exhausted by social activities. So I get both mental exhaustion and contamination at the same time.
Though interestingly, I do not suffer these mental fatigue and contamination symptoms during the social session itself; it is only in the hours and days that follows that I feel a feeling that the "essence" of people has intruded too deeply into my mind.
I would like to know the correct psychological classification for this type of mental state. What is it called when you feel somehow contaminated by people's essences, or the essences of places?
If it were possible to find the right
DSM classification for this mental disorder/symptom, then I think it may help in terms of identifying useful medications and treatments, and may help in terms of working out what the biochemical underpinning of such mental symptoms might be.
In some sense, this intrusion of other people's essences and energies into your own my feels like is a result of your own personal value system / belief system not being properly "firewalled" against external value and beliefs from other people.
Because of this weak mental firewall, you absorb too much of the essences and characteristics of other people, and the general conversation disturbs the order in your mind, so that you then need to spend some time on your own, so that you can slowly reinstate you own self, and return the mental chaos caused back to order.
One consequence of this condition is that it tends to make me less tolerant and more argumentative and more bigoted, which I don't like at all, because I used to be a very broad minded, accepting and eclectic person.
But I think I may have developed this intolerant argumentative disposition to protect my mind from the values and beliefs of others, in an attempt block what feels like the contamination of my mind by other people's views and opinions. Certainly the fault lies with me, regarding my argumentative disposition: this arises out of the frailty of my mind; it is not the fault of others.
I also found that very low dose (12.5 to 25 mg a day) amisulpride does provide some "padding" for the mind, in that this drug helps cushion against other people's essences and energies. And I also found that amisulpride increased my sociability (my desire to socialize). My sociability which plummeted quite low after a developed ME/CFS from a chronic viral infection.
(Incidentally, fortunately I don't think I developed tolerance to amisulpride, but I read that one way to sidestep the tolerance is just to take amisulpride only every other day.)