Active b12s startup for people with big reactions
ACTIVE B12S STARTUP FOR PEOPLE WITH BIG REACTIONS
Version 1.0 08/28/09
Up until now I have been focused mainly on people being able to tell if lack of b12 was the problem. There was a 5 item test protocol to detect that. It was not designed for a gentle startup. Just the opposite, it was meant to provoke maximum response quickly in as many people as possible so that they would know what the problem was. Generally those who had an overwhelming response had to experiment to try to find a way for minimizing these reactions. Having encountered a number of people recently who have had extreme reactions from starting up active b12s, which while it does indicate a severe shortage of those active b12s as there is nothing at all to indicate that they are not severely deficient in certain functional and possibly fundamental ways. Functional deficiencies are things that can change almost immediately; increases in neural transmitters, nerve speed, energy generation, some sensory things and a limited increase in methylation capacity. If taken with methylators such as SAM-e and methylfolate it can be like starting the engine with the accelerator floored and keeping it there. People who have been taking at least cyanob12 without methylators appear to become very deficient in methylation capacity. As we perceive percentage differences, even a small increase is perceived as huge. If we increase from 0.1% to 1%, that is a tenfold increase and is perceived as a huge increase, much larger than going from 1% to 2%. Doublings are only 3 just noticeable differences. Going up 10x is more than 3 doublings. Going from 50% to 100% is only one doubling and is not perceived as very much. As we increase our level of various things the amount of relative differences falls off.
With all that in mind then this is a first attempt at a reaction minimizing approach. It may not be suitable for everybody and is experimental in nature attempting the solution of this problem.
1. Discontinue SAM-e, methylfolate, TMG, L-carnitine, for 2 weeks in an attempt to cool down the methylation and enhancement of mitochondrial function. Also discontinue any glutathione and/or glutathione promoting precursors including un-denatured whey, glutamine, NAC, etc
2. Discontinue hydroxyb12 and/or cyanob12.
3. At the same time start taking Jarrow B-Right which includes a minimal amount of mb12, a&d, e, c, omega3 oils, calcium, magnesium, POTASSIUM and other basic supplements that are methylation and mitochondria neutral.
4. After one to two weeks off of the mitochondrial enhancers start Country Life Dibencozide (adenosylb12) retaining for 45 minutes or longer under upper lip. Adenosylb12 may cause an energized feeling. That is normal. When your mitochondria increase from 1% active to 10% or 20% or 50% you will notice a difference. It may seem jittery at first, the farther down you have been the more intense it will feel. It will feel normal after a while, days weeks or months. It may feel comfortable long before it feels normal. This is what becomes “normal” energy. Many miss it after it has begun feeling normal. With 1- 3 adb12 tablets the first day there will usually be no perceptible change after that from a daily tablet. Adb12 is not involved with methylation cycles or anything else. It only causes the mitochondria to work normally, nothing else.
5. After becoming comfortable with the change from the adb12, one can add the methylb12. Two weeks gets those other methylators mostly out of the system. If they were not being taken, it can be the next day or week or whenever you are comfortable with the adenosylb12. These things cause change. The ONLY things b12 does are the functional things it can do. It’s not like a drug that forces a reaction. It allows the body to function towards normal. Look at it this way. Let’s say, for the sake of a number, that there are 1000 units of startup functioning to get out of the way; no way to avoid that. If you start up 1 or 2 units a day it can take years. If you start up hundreds each day there is more intensity more quickly. It goes to 100%, no farther. It’s the same problem; going from 0.1% to 1% is as large a change as going from 1% to 10% or 10% to 100% as perceived intensity appears to be based on percentage of change over previous. No change produces no intensity. Change below a certain level, a Just Noticeable Difference can’t be perceived even if it occurs. If you are apprehensive about a large change, start with a crumb (really, just a crumb, 1/16 of a tablet for instance) of a 1mg tablet (Jarrow or Enzymatic therapy) under your upper lip for 45 minutes or longer or until gone. If you are going to feel it in any perceptible way you will by the time it fully dissolves and is gone. Intensity stops increasing by the time it is gone. Keep repeating all day as comfortable. After a few days of crumbs, you can move up to 1/8 tablet, then ¼ and then ½ and finally a whole tablet. Same method with each size. Equilibrium will keep increasing with each dose increase up to perhaps 25mg/day with 5mg Jarrow tablets. That produces the maximum healing one can expect from sublinguals and is equivalent to 2 times 2.5mg SC mb12 injections per day approximately. Maintain 1 adb12 daily during all this. Most people find 1 or 2 5mg tablets daily satisfactory for maintaining healing. After that more cofactors will make a larger difference and the right balance has to be found. Some people find taking 25mg the first day and next few days gets the startup over with quickly. Most don’t find 25mg any more intense than 2mg. It fills up the need faster and so there is less and less difference each day very rapidly.
