The symptoms discussed here do not sound anything like B12 deficiency to me. The textbook symptoms of B12 deficiency are:
- extreme tiredness.
- a lack of energy.
- pins and needles.
- a sore and red tongue.
- mouth ulcers.
- muscle weakness.
- problems with your vision.
- psychological problems, which can range from mild depression or anxiety to confusion and dementia.
Reflux is not among the typical listed symptoms. According to ChatGPT:
The other issue is that many of the listed B12 deficiency symptoms are so broad that they apply to a million other diseases. I went through the path of wishing I had X number of easily treatable conditions, but when my ME/CFS symptoms ultimately didn't respond to those treatments, it took several years to accept it wasn't as simple as B12 or methylation.
A single digit number of people here in my experience have reported being cured or close to cured after various methylation protocols. If you literally lack the capacity of processing B12 in the small intestine due to pernicious anemia or some rare genetic factors, then yes, obviously this is as simple as supplementing B12 and supporting factors like potassium.
In most people who are sick with ME/CFS type symptoms, the issues with our bodies go far beyond lacking a single vitamin or two. Even a functional approach focused on supplements and vitamins is typically trial and error with dozens of different things. Over the years I have found *certain* things that worked for me in terms of supplements, but it was not like reading a textbook, more like trial and error.
The good news is that treatment with B12 is generally safe, so it doesn't do much harm to try it out. In my case supplementing with methylcobalamin resulted in both increased anxiety and fatigue, which didn't go away despite false hope given to me that it would be "temporary".
