Rufous McKinney
Senior Member
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Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of and finding treatments for complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia (FM), long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.
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Magenta above are the critter
It seems possible that a Protozoan could contain or possess virus's themselves
on the powerpoint i think it said "e..g. plasmodium" (malaria like)
I think it is a protective response. Ibut unlike dauer in which it’s protecting against starvation this one is protective against massive amounts of oxidative stressIt feels as if our bodies are trying to sabotage any effort to increase our activity levels, and I think this is partly why we've got stuck with the psychosomatic label. If you report this experience to a doctor who's trying to treat your symptoms, it can easily sound as if you've just come up with another excuse for avoiding activity.
I think it's a protective response; what worries me slightly is that we don't really understand whether or not it's an appropriate protective response.
Hyperosmotic stress is linked to many maladies, including acute and chronic, as well as local and systemic, inflammatory disorders. Hyperosmolarity triggers cell shrinkage, oxidative stress, protein carbonylation, mitochondrial depolarization, DNA damage, and cell cycle arrest, thus rendering cells susceptible to apoptosis. However, many adaptive mechanisms exist to counter the deleterious effects of hyperosmotic stress, including cytoskeletal rearrangement and up-regulation of antioxidant enzymes, transporters, and heat shock proteins.
Two recent puplications:if mecfs was a cytokine-problem, this should be known by now ?
i dont know, is it ?
Two large 2015 studies found a general pattern of down regulation in long term patients (Hornig, et al and Landi, et al)
Cytokines are any class of immunoregulatory proteins secreted by cells, especially immune system cells.[1] Cytokines are small proteins important in cell signaling that modulate the immune system
in red blood cell deformability
where are the trypanosomes ?
In the paper linked above (b) we find entries related to eye disease, diabetes, liver disease, inflammatory bowel disease and cardiovascular disease