• Welcome to Phoenix Rising!

    Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of, and finding treatments for, complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia, long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.

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  1. linusbert

    Allicin boosts antioxidants while beeing itself one

    i am studying allicin right now. found this interesting, its boosting catalase and SOD but also glutathione. it also can increase NO (nitric oxide). it also is a super killer against bacteria, kills even MRSA. its also a supply for sulfur. chatgpt has this to say about it:
  2. S

    Bad reaction NAC/Liposomal Glutathione Permanent Damage? :(

    Hey hope one of you can help me. I'm struggling with suspected long covid since 2021, alot of symptoms cleared but i still had severe brainfog/derealization and fatigue. Somebody recommended me to try Liposomal Glutathion and NAC cus they had seen great benefits from it. About 1.5 week ago i...
  3. MeMeMe

    Glutathione or no glutathione?

    Hi all I’ve had ME/CFS since July (undiagnosed). I started methylating a couple of weeks ago and I think it’s been helping. But something I’m not clear on is whether to add glutathione to the MTHF + MCbl. I’ve seen that Rich didn’t include it in the protocol, at least not in the simplified...
  4. Pyrrhus

    Low glutathione in ME/CFS brain: a pilot magnetic resonance spectroscopy study at 7 Tesla (Godlewska et al., 2021)

    Neurochemical abnormalities in CFS: a pilot magnetic resonance spectroscopy study at 7 Tesla (Godlewska et al., 2021) https://doi.org/10.1007/s00213-021-05986-6 This is a study that confirms Shungu's 2012 finding of lower levels of the key anti-oxidant glutathione in the brains of patients. A...
  5. Mr. Cat

    Glutathione causing anxiety/irritability

    Hello PR, I just started taking liposomal glutathione, which initially had some positive effects of clearing brain fog, and a feeling of well-being. However, soon it started causing anxiety, and then irritability, without the positive symptoms I experienced earlier. I'm pretty sure this doesn't...
  6. C

    The plausibility of NAC inducing b12 deficiency or 'methyl-trap'

    Hello everyone. I am writing because I am particularly interested in the evidence for NAC inducing b12/b9 deficiency. I have thus far given the forums a cursory perusal and I have gathered that the event of b12 deficiency is plausibly linked to previous NAC supplementation. I had b12 deficiency...
  7. P

    Poll: How Many of You Chelated Mercury and Cured Any Condition?

    For those who attempted a chelation protocol to remove mercury - and you succeeded in doing a minimum of 20 rounds of chelation - what was your result? I created a poll to capture that question. In the discussion: * State your disease or symptoms that made you believe you had a heavy metal...
  8. H

    Help - I've overdone something re methylation and I don't know what

    As the title suggests I've made some errors regarding methylation supplements and I have no idea what's going on or how to fix it. Any help would be much appreciated. The background to this is that I have SIBO and CFS, and have been getting a lot better after about 6 months on Ben Lynch's...
  9. G

    Tiny amounts of glutathione make me tired

    Glutathione is a double-edged sword for me. I have to take a tiny amount of liposomal glutathione (like less than a drop) and cycle it on and off each day to get any benefit. Even then, its really had to get right, and much of the time it makes me tired and irritable. When I do get it dialed...
  10. Sarah94

    Questions about Methylation

    I have seen "overmethylation" mentioned in a few threads and I want to ask what is it? How would you know if you were "overmethylating"? I am taking transdermal B12 (methylcobalamin) spray which I bought from Dr Myhill's online shop. She recommends 5-10 sprays daily. I'm currently on 6 sprays...
  11. Sarah94

    Glycine - advice please?

    I want to switch my magnesium citrate (400mg each night) to magnesium glycinate. Because I have been informed that citrate can contribute to glutamate which may have a negative effect on sleep. And people say that mag glycinate is generally the best for relaxing you and helping you sleep. I've...
  12. snowathlete

    Increased ventricular lactate in cfs III. cortical glutathione and oxidative stress

    http://www.ncbi.nlm.nih.gov/m/pubmed/22281935/ Increased ventricular lactate in chronic fatigue syndrome. III. Relationships to cortical glutathione and clinical symptoms implicate oxidative stress in disorder pathophysiology. Don't know if this has been discussed here before? AuthorsShungu...
  13. merylg

    Increased Ventricular Lactate in CFS