https://clinicaltrials.gov/ct2/show/NCT04855201
A Study to Evaluate ASP0367 in Participants With Reduced Maximum Oxygen Uptake Due to Poor Systemic Oxygen Extraction
https://www.mitobridge.com/about/science/
Interesting new trial by Dr Systrom in collaboration with Mitobridge.
Why...
Authors
Phillip Joseph,
Rosa Pari,
Sarah Miller,
Arabella Warren,
Mary Catherine Stovall,
Johanna Squires,
Chia-Jung Chang,
Wenzhong Xiao,
Aaron B. Waxman,
David M. Systrom,
Abstract
Background
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is characterized by intractable...
A Similar Kind of Exercise Intolerance is Found in Connective Tissue Diseases, ME/CFS and Long COVID
Results
The study found that the blood vessels of people with CTD did not dilate as much as the healthy controls. The CTD patients also displayed an “impaired stroke volume increase”. As their...
Hello,
So I got a prescription for Mestinon from my doctor to see if it helps with exertional intolerance (most notably pain/discomfort after exercise). I am freaking out about it though.
For those that are not aware, this drug has been linked as a causal factor in Gulf War Illness (GWI). This...
I noticed that Dr. David Systrom published a paper that resonates a lot with what I have been experiencing.
Persistent Exertional Intolerance after COVID-19: Insights from Invasive Cardiopulmonary Exercise Testing.
https://journal.chestnet.org/article/S0012-3692(21)03635-7/fulltext
They...
A new publication by the team of Phillip Joseph, Anne Oaklander, and David Systrom, which I personally find exciting.
Insights from Invasive Cardiopulmonary Exercise Testing of Patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (Joseph et al., 2021)...
Massachusetts ME/CFS & FM Association and Open Medicine Foundation Fall 2020 Event on Zoom October 24, 2020
Video 2: Presentation by Ron Tompkins and Q&A
Video 3: Presentation by David Systrom
Video 4: Presentation by Donna Felsenstein
Video 5: Panel Discussion...
This isn't about ME, but some of the patients had POTS, and this is discussed in the context of exercise testing. Thought the results might be of interest to some here.
I have pulled out one of the relevant sections and quoted it (below the abstract)...