This is the first poll I have ever created (and I am technically challenged with these types of things) so am hoping that it worked! I have been posting a lot about IV saline in @jeff_w thread but decided it was time to create my own thread and let him have his back! I also wanted to do a poll to hear as many reactions and experiences with IV saline as possible. Here is an overview of my experience: I had IV saline while in the hospital in Sept but while lying in bed over a very slow drip (6-10 hours) and did not notice any effects from it. Since leaving the hospital, I was given a prescription by my cardio for one liter of saline 1x/wk (over a three hour drip) at the outpatient infusion center of the same hospital. I had my first IV saline treatment and literally felt like a normal person for 48 hours. It was miraculous and I thought that combined with increasing fluids (Pedialyte and coconut water) plus taking low dose Midodrine, that I had found the miracle cure to increase my low BP and low blood volume. I was able to breathe better and it was easier to walk and carry things. The effect wore off in 48 hours so I was pushing to get my prescription increased to 3x/wk. Yesterday I had my second IV saline (exactly one week after the first) but not only did not get the positive reaction, I had a horrible increase of fatigue and a severe headache with pressure behind my right eye. My BP stayed in the 90's over 60's so there was no issue of my BP going too high. I also got very agitated last night and had a severe noise sensitivity reaction. I could explain the incident but the details are not that important. Is it possible to have that kind of bad reaction to one liter of saline (over a 3 hr drip) or does it seem more likely that I just crashed from 1-2 weeks of overactivity and unrelated to the saline? My doctor has been out of the country but ironically last night, through his PA, I got the approval to increase to 3x/wk starting next week. But now I am not sure if I should due to the weird reaction I had plus not getting the benefit. I know it could be a fluke and am planning to try it again just 1x next week, and if it goes well then increase to 2x the following week, and then 3x/wk times. On a side note, I have bad veins but the nurse at the infusion center is excellent and did not have any problems the two times I went. I would love to hear any feedback on how to proceed as well as other people's experiences with IV saline. And thank you to anyone who answers my very first poll! Question for @Sushi- Is there a way to add one more answer to my poll which is "IV saline had varying effects- sometimes I felt better, sometimes worse" or something to that effect? I can't figure out a way to edit my poll and realize I want that as one of the choices. Thanks!