You probably have an autoimmune disease...

[sometexan84]

Thx! Got it, and am adding more (editing other list)

 

[sometexan84]

Here's an updated list of the autoantibodies just from those in this forum.

The one at the very end (TS-HDS) is from me. I just got the positive results back. It's 1 of 2 new antibodies Cell Trend offers in their testing. I highly recommend getting the CellTrend tests done.

I wouldn't be surprised if we see a lot more positive results from PR forum members for the Small Fiber Neuropathy antibodies FGFR3 and TSHDS.

https://www.celltrend.de/en/pots-cfs-me-crps/

Autoantibodies in forum…

AChR Binding (acetylcholine receptor)
1x
Carbonic Anhydrase VI (CA VI) – Early Sjogren's Syndrome
1x
Myelin
2x
Basal Ganglia (ABGA)
1x
Myocardial Peptide
1x
Voltage-Gated Calcium Channel, N-Type (VGCC) - Lambert-Eaton myasthenic syndrome
1x
Beta-1 Adrenergic Receptor (β1AR) - Dilated cardiomyopathy
2x
Beta-2 Adrenergic Receptor (β2AR)
6x
Alpha-1 Adrenergic receptor (α1AR)
14x
Alpha-2 adrenergic receptor (α2AR)
5x
Ganglionic (alpha-3) Acetylcholine receptor (α3-AChR) - Autoimmune autonomic ganglionopathy
1x
Phosphatidylserine - Antiphospholipid Syndrome
1x
Endothelin-Receptor-A (ETAR)
7x
Angiotensin-II-Receptor-1 (AT1R)
7x
Muscarinic acetylcholine receptor, M1 (mAChR)
1x
Muscarinic acetylcholine receptor, M2 (mAChR)
5x
Muscarinic acetylcholine receptor, M3 (mAChR) - Primary biliary cholangitis/cirrhosis
3x
Muscarinic acetylcholine receptor, M4 (mAChR)
9x
N-methyl-d-aspartate (NMDA) receptor - (NMDA) Receptor Encephalitis
1x
Parotid Specific Protein (PSP) - Early Sjogren's Syndrome
1x
Dopamine Receptor 1 (DRD1)
1x
Tubulin
1x
Phospholipid - Antiphospholipid Syndrome
1x
Gliadin - Celiac disease
3x
Cardiolipin (aCL) - Antiphospholipid Syndrome
3x
ANA (Antinuclear Antibodies) - Lupus, Scleroderma, Sjögren's syndrome, Rheumatoid arthritis, etc
9x
Scl-70 (topoisomerase) - Scleroderma, Connective Tissue Disease
1x
SS-A/Ro (Sjögren's-syndrome-related antigen A) - Sjögren's-syndrome
3x
TPO (Thyroid peroxidase) - Hashimoto's
12x
Saccharomyces cerevisiae (ASCA) - Crohn's Disease
1x
CCP (cyclic citrullinated peptide) - Rheumatoid arthritis
3x
Parietal Cell - Pernicious anemia
3x
Smooth Muscle (SMA) - Primary biliary cholangitis, Autoimmune hepatitis
2x
GAD65 (glutamic acid decarboxylase 65) - Type 1 Diabetes
1x
Jo-1 (Anti-histidyl tRNA synthetase) - Myositis
1x
Proliferating cell nuclear antigen (PCNA)
1x
Mitochondrial (M7) (<< heart) - Myocarditis
1x
GABABR (gamma-aminobutyric acid B receptor) - GABABR encephalitis
1x
Salivary Protein 1 (SP-1) - Early Sjogren's Syndrome
1x
Thyroglobulin (TgAb) - Hashimoto's
4x
Beta-2-Glycoprotein I (β2GPI) - Antiphospholipid Syndrome
2x
Rheumatoid Factor
2x
Neurofilament
1x
RNP (Ribonucleoprotein)
1x
TS-HDS - Small Fiber Neuropathy
1x

 

[Boba]

I believe in Autoimmunity as well!! The only ones I know are TPO, but it just fits with everything .

 

[Learner1]

I believe in Autoimmunity as well!! The only ones I know are TPO, but it just fits with everything .

There are quite a few other autoimmune antibodies that are causing a lot of us a lot of problems. I believe TPO antibodies are T cell driven, while most others are B cell driven.

 

[godlovesatrier]

Just got my results for auto immune panel back. ANA was negative, as were the other 6 antibodies I got tested. So no clearer on what causes my symptoms but it does rule a few things out.

 

[ChookityPop]

Just got my results from Celltrend. TS-HDS positive.

 

[Boba]

Just got my results from Celltrend. TS-HDS positive.

That’s SFN right? I will get mine checked next week.

 

[Zebra]

For those of you in the United States, you can get FGFR3 and TS-HDS antibody testing done through the Neuromuscular Laboratory at Washington University in St Louis.

Your doctor will need to download and complete a Wash U requisition form, which you then take to a local hospital or clinic that you have verified is capable of sending your blood to Wash U. This is most easily done at a university-based hospital, but you can phone around to local hospitals, clinics, and labs as well.

Link to PDF requisition form & instructions.

https://neuromuscular.wustl.edu/lab/reqs.htm

 

[ChookityPop]

That’s SFN right? I will get mine checked next week.

Yes this is Small Fiber Neuropathy. FGFR3 and TS-HDS.

 

[sometexan84]

Just got my results from Celltrend. TS-HDS positive.

TS-HDS Buddies!!

Weren't we already thinking that might be the case for you? I can't remember.

 

[ChookityPop]

TS-HDS Buddies!!

Weren't we already thinking that might be the case for you? I can't remember.

Yes we did! The health care system havent found a single thing in 7 years so its pretty satisfying to finally find something.

 

[Martin aka paused||M.E.]

I've tested for the Scheibenbogen GPCR (ELISA, no BioAssay) and the results were negative. ANA is 1:80. Dozens of neuro(-muscular) AAB were tested in a hospital... All negative. SLE I'm not quite sure about those bc the results were contradictory. But I don't by think I have SLE.
Topic that came up today with the new Fluge and Mella study in a discussion about Abilify: AAB to D2 receptors. That would be interesting to investigate.
https://pubmed.ncbi.nlm.nih.gov/30427893/

 

[Fogbuster]

What kind of specialist tests for autoimmune antibodies?

 

[crypt0cu1t]

What kind of specialist tests for autoimmune antibodies?

Usually rheumatologists or neurologists occasionally

 

[sometexan84]

Usually rheumatologists or neurologists occasionally

This is pretty true, but there's about a 1% chance they'd ever test anything in the CellTrends panel, let alone TS-HDS antibodies. You can get this done yourself though

 

[Jadzhia]

I have Hashimoto's and I have raised TPO antibodies and TG Antibodies (thyroglobulin). They've stayed around the same level for the past few years. I need to re-test soon, actually. During that time I've had all sorts of dietary and supplement changes - nothing has affected them either way.

 

[sometexan84]

I have Hashimoto's and I have raised TPO antibodies and TG Antibodies (thyroglobulin). They've stayed around the same level for the past few years. I need to re-test soon, actually. During that time I've had all sorts of dietary and supplement changes - nothing has affected them either way.

If it makes you feel any better, I didn't have any symptom improvement at all when my Hashimoto's finally went into remission.

Just too much other stuff going on in my body I suppose.

 

[georgina699]

I recently tested positive for ANA and Speckled Pattern, but my PCP did not give me a diagnosis. She'll be referring me to a specialist. I am scared but a tiny part of me stupidly was glad they found something...

 

[georgina699]

You can get this done yourself though

how much does it cost?

 

[SWAlexander]

I recently tested positive for ANA and Speckled Pattern, but my PCP did not give me a diagnosis. She'll be referring me to a specialist. I am scared but a tiny part of me stupidly was glad they found something...

So am I and many more. No diagnosis and no explanation from the doctor what these tests could mean.