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Why would Niacin cause depression?

Messages
12
This is a very old post, but I'm currently experiencing the same so I thought I would comment as it seems to be the only place people have expressed the same reaction. I was suddenly hit with anxiety and depression after taking niacin. It's been a week now. So upsetting considering I was in good spirits before.

I'm testing for methylation. My blood test results for b12 were normal/low range at 290... Perhaps taking b12 would help.