garyfritz
Senior Member
- Messages
- 599
As far as I know, I don't have ME/CFS. I always had low energy but I considered myself pretty healthy. I had RLS (restless legs syndrome) since childhood, and a nagging occasional problem with sleep for the last 20 yrs where I would wake with twitching muscles and agitation, but that was about it.
But over time I keep getting worse. The sleep issues got worse over time, and started migrating into daytime agitation, feeling almost like a constant fight-or-flight reaction. By last summer it was getting pretty bad, but fortunately my naturopath suggested B12. I started taking 500-1000mcg/day of Readisorb liposomal methylB12, and poof! All symptoms completely disappeared. It was miraculous. For 6 months.
The problems started coming back, and I found this place. I started boosting my mB12 up to 20mg/day, adding adB12 (4mg/day), methyl folate (4-5mg/day), LCF. I had the problem totally under control. I would generally sleep through the night. If I woke up I was generally agitated/twitchy and I couldn't go to sleep on my own, but if I popped a 5mg mB12 (Country Life) I would be asleep before it dissolved. That lasted another few months.
In the last few weeks I've been having more and more trouble. This past week was bad, and last night was terrible. I was awake 2-5am, agitated but not as twitchy as I used to be. I took 10mg mB12 and 2mg adB12 before I could relax enough to drop off. Got a few more hours of fitful sleep but I've felt crappy all day: achy, woozy, hyper-ish, exhausted, just yuck.
So apparently I need to figure out what I need to fix it this time. More mB12? More mfolate or adB12? I don't know. More importantly, I don't know how long the next fix will last -- or if I can keep finding fixes.
Why do I keep getting worse? Why can I find something that appears to fix the problem 100%, but it only lasts for a few months or weeks?
If B12 was a drug, I would say I was building up a resistance to it. My son suggested going cold-turkey for a week to see if it reduced my resistance. I told him I would be a basket case if I went without for a week -- I wouldn't get much sleep at all, and what I got wouldn't be restorative. I would be a vibrating, twitching, hyper-stressed mess. But in any case, B12 isn't a drug, it's a vitamin. I shouldn't get "resistant" to it any more than I get resistant to food.
Has my body been starved for B12 all my life (I'm +/+ MTHFR and others, see below), and now I've awakened the beast and it wants more, more, more? Why do I feel worse than I did 18-20 months ago? I'm packing in tons of methylation support now, and it seems to have a huge positive effect, but it never lasts for long. And when it quits working, I feel MUCH worse than I did two years ago. Am I going to continue to get worse and worse?? Is there any way to get this under control and KEEP it controlled?
Thanks for any insights anyone might have...
Gary
But over time I keep getting worse. The sleep issues got worse over time, and started migrating into daytime agitation, feeling almost like a constant fight-or-flight reaction. By last summer it was getting pretty bad, but fortunately my naturopath suggested B12. I started taking 500-1000mcg/day of Readisorb liposomal methylB12, and poof! All symptoms completely disappeared. It was miraculous. For 6 months.
The problems started coming back, and I found this place. I started boosting my mB12 up to 20mg/day, adding adB12 (4mg/day), methyl folate (4-5mg/day), LCF. I had the problem totally under control. I would generally sleep through the night. If I woke up I was generally agitated/twitchy and I couldn't go to sleep on my own, but if I popped a 5mg mB12 (Country Life) I would be asleep before it dissolved. That lasted another few months.
In the last few weeks I've been having more and more trouble. This past week was bad, and last night was terrible. I was awake 2-5am, agitated but not as twitchy as I used to be. I took 10mg mB12 and 2mg adB12 before I could relax enough to drop off. Got a few more hours of fitful sleep but I've felt crappy all day: achy, woozy, hyper-ish, exhausted, just yuck.
So apparently I need to figure out what I need to fix it this time. More mB12? More mfolate or adB12? I don't know. More importantly, I don't know how long the next fix will last -- or if I can keep finding fixes.
Why do I keep getting worse? Why can I find something that appears to fix the problem 100%, but it only lasts for a few months or weeks?
If B12 was a drug, I would say I was building up a resistance to it. My son suggested going cold-turkey for a week to see if it reduced my resistance. I told him I would be a basket case if I went without for a week -- I wouldn't get much sleep at all, and what I got wouldn't be restorative. I would be a vibrating, twitching, hyper-stressed mess. But in any case, B12 isn't a drug, it's a vitamin. I shouldn't get "resistant" to it any more than I get resistant to food.
Has my body been starved for B12 all my life (I'm +/+ MTHFR and others, see below), and now I've awakened the beast and it wants more, more, more? Why do I feel worse than I did 18-20 months ago? I'm packing in tons of methylation support now, and it seems to have a huge positive effect, but it never lasts for long. And when it quits working, I feel MUCH worse than I did two years ago. Am I going to continue to get worse and worse?? Is there any way to get this under control and KEEP it controlled?
Thanks for any insights anyone might have...
Gary