Why did paracetamol clear my PEM?

[gm286]

It's been a few weeks where I've been trying to work through dosages and new medications, seeing what could possibly help my PEM (aripiprazole, anti-histamine, B2, SAM-e).

Nothing has really worked lately except for today -- attempted paracetamol after my stomach was feeling slightly achey / acidic from a meal. This last period I have also had an IBS flare, perhaps due to the high vitamin B2 supplement or some other medication's effect.

I was feeling really brain fogged and with some significant amount of PEM. Picked up paracetamol (sublingual powder) since I was running errands while at work. The paracetamol did two things: instantly pull me out of PEM / brain fog and revert my IBS flare.

This has happened to me once or twice before (where I really took notice that it was overtly and expediently helping my symptoms). Has this been the case for anyone else? The drug is extremely common. Therefore, I wondered if someone benefited at one point or another from paracetamol and if they had clues as to its mechanism for ME/CFS and PEM. The effect was not just temporary (a few hours) but lasted throughout the day and allowed me to expend energy properly, and sharply.

 

[ljimbo423]

Has this been the case for anyone else?

A member here, Murph, has had good success at relieving PEM with paracetamol. Here is a link to some of the posts he has made-

https://forums.phoenixrising.me/search/491262/?q=paracetamol&c[users]=Murph&o=date

 

[ljimbo423]

The paracetamol did two things: instantly pull me out of PEM / brain fog and revert my IBS flare.

I find it really interesting that the paracetamol not only got rid of your PEM but also your IBS flare. Has it helped your IBS before?

 

[gm286]

@ljimbo423 This is the first time that I outright notice it has helped my IBS. I'll try to keep track of this and update accordingly.

 

[Alvin2]

No effect on my end. In fact it is a poor pain reliever, i use Naproxen most of the time. Though for some types of pain it works well in combination.

That said glad its working for you.

 

[Alvin2]

In your honour i am taking 500mg now to see if it will affect my current PEM.

If this is my last post you will all know why (sarcasm)