@Mrunknown I've seen the Human RNA Rumor Viruses paper before, good reference and interesting. As far as autoimmune, was tested for a number of things but symptom wise, Sjogren's fit because of dry mouth but more rare in males and test was negative. No other autoimmune disease was diagnosed either. Haven't had any opportunistic infections diagnosed. Various symptoms have been acknowledged and medications offered. For example, was offered some saliva stimulating medication for dry mouth but it came with risks and didn't address the root cause so I opted to just use xylitol lozenges instead.