hi rich, in the start of this thread you mention excitotoxicity, im wondering your opinion on amino acid phenylalinine(spelling??) causing this as its present in a lot of diet soft drinks. Do u have an opinion on injectable hydroxycobalmin, also i have access to a formula that contains 500mcg of hydroxy and 15mg of folic acid per ml. Also with other nutrients that you mention , in particular different amino acids, if on a high protein diet, is there a need to supplement these as most of these aminos are in meat as well as alot of b vitamins. Just as a point of interest, vegetables are considered high in vitamins but most only contain a few where as meat seems to contain a high content of many nutrients, the only one i can see that maybe lacking is vitamin c which is easily supplemented with and cheap as chips. I understand that b12 is high in meat but is subject to absorption factors as in pernicious anemia. i have had some success with b12 injections(at one time was using hydroxy 5000mcg 3 times a week), i folllow a high protein diet aka atkins style and was using alot of diet soft drink but after cutting back (no caffeine) i havent found it affecting my sleep(insomnia) in any positive way. Supplement wise i use fishoil, vit e and c, d, nac, lipoic acid and whey protein. One more question, do u know if they do the vitamin type testing u mention in australia. What a loaded paragraph ive written, dont think i could add too many more questions, lol!!!
The aspartame in diet soft drinks is composed of phenylalanine and aspartate. As far as I know, phenylalanine is not an excitotoxin, but aspartate is. Dr. Amy Yasko recommends no consumption of aspartame for people with autism or other disorders that involve methylation cycle dysfunction.
I think injectable hydroxocobalamin is fine to use as part of the protocol for treating the partial methylation cycle block in CFS. I prefer reduced forms of folate, rather than folic acid, but if a person has inherited a relatively fast form of the DHFR enzyme, and also does NOT (added in editing) have SNPs in the SHMT or the MTHFR enzymes, I think that folic acid could work, if used in high enough dosages. There is a company in New Zealand that distributes Thorne Research products in Australia, and one of them is 5-MTHF, which is a better form of folate to use, in my opinion.
Whether or not one needs to supplement amino acids if one is on a high-meat diet would depend on how well the digestive system is able to digest protein and absorb amino acids.
I know that the Metametrix Lab serves Australia, and they offer testing that includes information that will indicate vitamin deficiencies. Also, the Health Diagnostics and Research Institute in New Jersey, USA (formerly Vitamin Diagnostics) does receive samples from Australia, and they specialize in vitamin testing.