PACE spent 8,000 pounds per person (641 people) and was low tech/no tech.
How on earth could MEGA study 12,000 samples?
Peter White has been talking about a study like this for years- looking at biomarkers for stress, fatigue, depression, anxiety.
MEGA does not look like a study on ME/CFS at all.
Studies of ME/CFS actually need to look at ME/CFS symptoms - and should not focus on comorbid mental health issues as MEGA does.
Unless every person meets the CCC plus PEM or ICC its a total waste of money and may be harmful.
Money needs to be targeted to where it has a good chance of finding pathophysiology and biomarkers.
The knowledge of ME/CFS is far too limited at this stage to do a broad study.
Each phenotype once identified by biomarkers can be removed from the general ME/CFS pool..
How on earth could MEGA study 12,000 samples?
Peter White has been talking about a study like this for years- looking at biomarkers for stress, fatigue, depression, anxiety.
MEGA does not look like a study on ME/CFS at all.
Studies of ME/CFS actually need to look at ME/CFS symptoms - and should not focus on comorbid mental health issues as MEGA does.
Unless every person meets the CCC plus PEM or ICC its a total waste of money and may be harmful.
Money needs to be targeted to where it has a good chance of finding pathophysiology and biomarkers.
The knowledge of ME/CFS is far too limited at this stage to do a broad study.
Each phenotype once identified by biomarkers can be removed from the general ME/CFS pool..