That's not what SOC found. She found only very high doses of Q10 reduced her PEM. See her threads.
I really don't care what SOC is taking. She is not me, and does not have my genetics or my mitochondria. I need to take a dose that's right for me.
It's not correct to assume that when someone takes a supplement at a dose which satisfies their daily nutritional requirements, increasing the dose above that will have no further effects. Sometimes new effects are only achieved by going well beyond the recommended daily nutritional requirements.
Totally agree.
In terms of the safety of high Q10 doses, according to
this article:
There are other articles that say differently. They say that 100 to 300 mg is a standard dose, or 100 to 200 mg. I almost quoted one of those but didn't. What matters is what works for a given individual.
If you are only taking low doses of Q10, then you are not really following the protocol discovered by SOC. So therefore you have not properly tested this Q10 protocol for its possible PEM relieving effects.
This is what my most recent testing says:
I'm hard pressed to see that going above this level will be more beneficial for me.
CoQ10 will help if one needs it. However, after a lot of experimentation, and informed by my testing which showed that I have huge oxidative stress, for me, I have found that adding Setria glutathione before and after exercise has helped me avoid and has helped me reverse PEM when it happens. I currently take 2.8 grams a day in two 1.4 gram doses. I also found that increasing ALA, A, and E had a positive effect on my energy. And that taking NMN first thing in the morning, as well as if my energy is dipping is helpful too. This all works If I have enough thyroid hormone and hydrocortisone in my body, not an excessive amount, just enough to bring me up to "normal."
in the past, I was short of isoleucine and leucine, and during that lengthy time period, I found that BCAAs taken with the glutathione helped PEM as well, But my testing in the past several months showed that I was replete in these amino acids, and so I was able to drop them, as they did not seem as effective as they had in the past.
So, while I'm very excited for SOC's success with CoQ10, there are many other factors that can lead to PEM and reverse PEM.