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No one said metabolic trap is unreliable. Dr. Davis said that mass spectometer is not accurate enough for their taste and they have to develop a new way to do it where precision will be satisfactory to them.
Also, please remember that both Dr. Davis and Dr. Phair made it very clear during the Symposium that metabolic trap is an unproven hypothesis and could be wrong, as promising as it is.
Don't put all your hopes in it, rather put the hope in the rising number of researchers joining our fight and the hard work everyone is putting in it.
This is a difficult time for all of us and it's alright to take a break.
However, everyone who is frustrated with slow research should put more pressure on NIH director, not take it out on researchers who are actually the only ones giving us real tangible hope right now.
Your anger and disappointment is justified, but you're taking it out on the wrong people.
I'm being honest and hugely disappointed. The highlight and big star of the Symposium was the trap and now we are told it's unreliable. I'm not blaming the Researchers, I know they are trying but I myself feel like stopping following the whole thing. @Ben H you forever put a shine on things when some of us are hanging on by a thread. Donating, donating endlessly. Nancy Klimas said in a recent video she was closer than anyone to solving this, I've asked a number of times why OMF don't work with her and help her get trials off the ground. She is ready for clinical trial so why not work with her? Ready for trial @Janet Dafoe (Rose49) . I can't understand why there is no link up.
I'm not aware of Dr. Klimas having identified a specific trap, is there some source on that? The trap that OMF has identified is a problem with a tryptophan pathway and I'm not aware of anything specific like that being identified in other research.
Trap, new homeostasis, system reset, whatever term you want to call it... Nancy uses different terminology. It's all the same idea.
It's not the same idea. I don't know where you got that from.
They might be looking at different biology (Kynurenine/HPA axis) but it's all under the idea that 'we are in a trap/hole/disease state'
Sorry that Ron looks so flat--just exhausted mentally and spiritually--hope he can get some rest.
I think that's partly just his mannerisms - not to say he's a "flat" or "low-energy" guy, but he has kind of a monotone way of speaking that makes him appear more tired than he actually is. When I talked with him a few months ago he was very switched on for a long time and I came away with the impression I had just spent time with a very driven, very intelligent person. I'm sure anyone would be tired with the demanding task he has to face, and I'm glad it's him as opposed to some of the "energetic" salesperson personalities that have cost patients millions of dollars selling snake oil.
It's not the same idea.
It has one similar part - that there is no pathogen but that our bodies themselves have a fault that keeps us sick (as do countless other diseases).
Other than that those are three very different hypothesis, with different triggers, different causes, different disturbances keeping us in this state and, most importantly, which would require vastly different cures.
They have chosen different pieces of the same concept to attack.
Not really.
Reseting HPA axis, turning off cell danger response and lowering the amount of tryptophan in cells are not different pieces of the same concept.
Never say never, so maybe some day far down the line they find something in common, and it's not necessary for all the others to be completely wrong once one hypothesis proves to be right, but right now they are working on vastly different concepts, in different parts of the body, and solving them in different ways.
I am still not sure where you got the idea it's the same thing, especially after Dr. Dafoe clearly said in this thread that Dr. Phair and Dr. Davis are the first ones to work on metabolic trap hypothesis.