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Sleep deprivation impairs molecular clearance from the human brain 2021

pattismith

Senior Member
Messages
3,941
Sleep deprivation impairs molecular clearance from the human brain
Per Kristian Eide, Vegard Vinje, Are Hugo Pripp, Kent-Andre Mardal, Geir Ringstad
Brain, Volume 144, Issue 3, March 2021, Pages 863–874, https://doi.org/10.1093/brain/awaa443
Published:

23 March 2021
https://forums.phoenixrising.me/javascript:;
Abstract
...

One night of sleep deprivation impaired clearance of the tracer substance from most brain regions, including the cerebral cortex, white matter and limbic structures, as demonstrated on the morning of Day 2 after intervention (sleep deprivation/sleep).

Moreover, the impaired cerebral clearance in the sleep deprivation group was not compensated by subsequent sleep from Day 2 to 3. The present results provide in vivo evidence that one night of total sleep deprivation impairs molecular clearance from the human brain, and that humans do not catch up on lost sleep
 

Alvin2

The good news is patients don't die the bad news..
Messages
3,024
So one night of impaired sleep screws the brain for life?
Or do they need to look past 3 days?