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Sildenafil on its effects on Fatigue, Cerebral Blood Flow in ME/CFS

Springbok1988

Senior Member
Messages
160
I recently started on daily tadalafil 5 mg to see if it helps any of my symptoms. Today is only my fifth day on it but I have seen mild improvement in some of my symptoms. My brain fog seems slightly better. I also have this strong oppressive feeling in my head that has improved some. I don’t know how to describe the feeling other than that. My head just feels more “open” now and I feel like I can relax a bit more.

I’ve had two side effects so far: headaches and eye pain. I read that this normally goes away after the first week.

I am moderately-severe to severe and haven’t seen any improvement in fatigue or other symptoms.
 

Remi

Senior Member
Messages
172
I recently started on daily tadalafil 5 mg to see if it helps any of my symptoms. Today is only my fifth day on it but I have seen mild improvement in some of my symptoms. My brain fog seems slightly better. I also have this strong oppressive feeling in my head that has improved some. I don’t know how to describe the feeling other than that. My head just feels more “open” now and I feel like I can relax a bit more.

I’ve had two side effects so far: headaches and eye pain. I read that this normally goes away after the first week.

I am moderately-severe to severe and haven’t seen any improvement in fatigue or other symptoms.
How are you doing now? I have a sort of tension on my crown when I try to think. Severe brainfog, too.
 

Springbok1988

Senior Member
Messages
160
How are you doing now? I have a sort of tension on my crown when I try to think. Severe brainfog, too.
It’s still helping, which is surprising because most things that have helped have stopped working after a week or two. My insomnia initially improved and I got several days without using a sleeping medication for the first time in my adult life but my sleep has gradually worsened back to where it was before I started on it.

My head still feels more open and I still am able to relax a bit more than before. I might try sildenafil at some point but, until then, I plan on staying on this medication.
 
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