Of course, patients who are exposed to both mold and viruses may have a combination of CIRS and ME/CFS, so perhaps it may not always be a clearcut case of whether you have either CIRS or ME/CFS; you may have a bit of both.
So Shoemaker says that in these genetically susceptible patients, mycotoxins and other biotoxins are not detoxified. The genetic susceptibility Shoemaker refers to relates your HLA DR genotype: Shoemaker say that 24% of the population have the genotype that makes them unable to properly detoxify mycotoxins and biotoxins. Shoemaker's treatment is to use cholestyramine, which binds to the mycotoxins in the intestines, and pulls them out of the body.
I was not able to try CSM (cholestyramine) at that time b/c my MCAS was so severe and my mold doctor felt it was too dangerous for me. I tried activated charcoal, bentonite clay, but could not tolerate micro dose (at that time) b/c of my MCAS. I ended up using Nebulized Glutathione (which was very helpful) and very gentle binders like oats and apple pectin. I did this for about 9-10 months approx.
Do mycotoxins contain antigenic regions that the immune system would recognize and produce antibodies against?