That was a really interesting link about "Neuritin" and I book-marked the site on my computer. I also Googled "Neuritin" and got a bunch of ads for Palmitoylethanolamide (PEA). Are they the same thing?
I think PEA is unrelated, but Google is matching the closest ads it has for neurological disorders.
Neuritin isn't just an immunomodulator.
"Neuritin has several effects in the nervous system, such as promoting neurite outgrowth, modulating neurite outgrowth during neuronal differentiation, protecting motor neuron axons, promoting dendritic growth, shaping dendritic arbors of target neurons, regulating synaptic plasticity, stabilizing active synapses, promoting synaptic maturation and neuronal migration, promoting the development and maturation of visual cortical neurons, regulating apoptosis of proliferative neurons, and regenerating peripheral nerve and spinal axons."
Maybe ME alters the amount of neuritin in our brains, altering neural functions? It seems a good candidate for measuring in PWME vs controls.
Simple experiment (assuming neuritin is available for human use): give a PWME an injection and see if their symptoms decrease. If it works, it deserves funding for a proper study. Skip spending millions on studying whether it's theoretically worth trying on animal and then human subjects.