I took so long to reply sorry - I am also confused about the Nancy Klimas and others suggesting the breaks - the first time when I came right in 16 months I took it everyday - it was early days ie 5 years agao. Now I take 6 perday but everynow and then have a break in the weekends. My doc says she doesn't know why the break but as I was usccessful? last time to take it everyday. Also on another thread have found a cheaper source from Goldpharm. Look it up - I'm thinking I will try to find out more about it as it is half the cost of getting it from my pharmacist.Hi Frankie, thanks for sharing your experience. Did u take 6 tabs a day all the time or did u alternate your doses and had periods of severals months where u took a break from it. Info that i have read on dosing seem to suggest alternating doses each week and using 2 months on and 2 months off. Yes immunovir is expensive, cycloferon seems cheaper and doses recommended are alternated. Im unsure of the reason for alternating doses for immunomodulators, I think its to help avoid tolerence but got no real idea why.