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Potassium Block l-Methylfolate?

Messages
70
Could someone please clear up for me , if Potassium supplementation(possibly within 5mthf's 3 hour halflife) can block l-methylfolate absorption?

i believe ive read Freddd state this before; but i very possibly read it wrong..
 
Messages
70
Let's look at the half lifes then. While 99% of the B12s are out of the body in a day, it takes about 3 days for b12 deficiency symptoms to start getting worse after a number of doses. The AdoCbl has a 99% loss from the bloodstram in 24 hours BUT once it is in the mitochondria it appears closer to 71 day tissue halflife. The l-methylfolate has about 3 hours halflife. I go into folate insufficiency simply by missing a single dose or having it blocked by potassium.
Freddd
said the above in post #8 on this page http://forums.phoenixrising.me/inde...-smp-preferable-to-just-take-b12-first.22213/
 

SJB944

Senior Member
Messages
178
Anyone else also experienced potassium blocking methyfolate? Do you have to take them apart, I've never seen any explanation of this @Freddd ?
 

Mary

Moderator Resource
Messages
17,287
Location
Southern California
I've been taking methylfolate and potassium together for the last several years with no problem (that I know of!) Maybe I'd absorb the methylfolate better taken separately from potassium, though I don't seem to have any absorption problems. I do need a fair amount of potassium since starting the methylfolate, however.
 

SJB944

Senior Member
Messages
178
Thanks @Mary me too. I've been taking together for some years, and more recently taking methylfolate sublingually, which I noticed was an improvement -- but then I was wondering if the block only occurred when taken together orally.
 

Mary

Moderator Resource
Messages
17,287
Location
Southern California
Thanks @Mary me too. I've been taking together for some years, and more recently taking methylfolate sublingually, which I noticed was an improvement -- but then I was wondering if the block only occurred when taken together orally.

Interesting - what brand sublingual methylfolate do you take? It might be worth an experiment for me to try it! :)
 

SJB944

Senior Member
Messages
178
I actually just use Solgar Folate (metafolin) but place it under my lip and let it dissolve -- it seemed to produce better absorption.