In my 18 years of ME, I found two things by accident which made a big improvement in my quality of life. T2 or iodine, taken one dose every 21 days prevents a worsening of my symptoms. Cumin (Cuminum cyminum) was a very effective PEM blocker for me. After taking it every three days for about two years, it seems that my physically-induced PEM is permanently blocked. Wonderful stuff...for me. Sadly, neither of these treatments have worked for anyone else. It does show that it is at least possible to discover some treatments that can work effectively, even if it works only for one individual. If you try exotic foods and herbs&spices and supplements, or maybe even weird flavours of jellybeans, maybe you'll find something that works for you.
The other treatment I accidentally discovered cured the type IV food sensitivity that started with my ME. Canned coconut milk that proved to be 'a bit off' flushed that sensitivity right out. Two and a half years of triggering on most foods disappeared down the toilet, so to speak. I'm not proposing it as a reliable treatment though.
I've recently discovered that Evening Primrose Oil seems to improve my sleep, reducing the chances of insomnia. I'm not sure whether that insomnia is related to ME, since it didn't start until year 16 or so, but insomnia doesn't seem beneficial for ME, so avoiding it is good.
All of these were accidental discoveries. I can't think of any basic, logical things such as good sleep regime or healthy diet that made a difference. No, wait, I can think of one:
avoid things that make your symptoms worse.
