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Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of and finding treatments for complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia (FM), long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.
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I initially started with gum, found the choline was an issue (choline bitrate apparently wasn't working for me) and then used 7mg patches for 2 weeks.What was your dosage? Did you wear the patch for 24 hours, or did you play with removing it at night? I'm sorry it's not working out.
AFAIK this isn't about cigarette smoke at all but rather properties of nicotine, primarly via nicotine patches and AChR.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC423647/
Cigarette smoke can activate the alternative pathway of complement in vitro by modifying the third component of complement.
It's a line of thought that has to be mentioned. Alot of fuzz about nicotine patches and a lot of research and hypotheses on Herpesviruses in LC/ME/CFS and seemingly no information on the two (you were the first who I've read mention it). Did you manage to get your EBV levels tested or was your reactivation based on your previous experiences and the typical symptoms of EBV (swollen lymphoids etc)?Nicotine also reactivates herpes virus according to one study. Maybe if you're in the very early years of illness as with LC you can stil tolerate nicotine. We will see.