New treatment being researched: Inspiritol—Today’s Press Release

[EtherSpin]

I think many of us disregard it because it's just specific proportions of supplements many of us have already tried. Since ME varies so much between victims, it's highly unlikely that any precise and specific proportion of common supplements would work for many people while slightly different proportions wouldn't.

I see your point.

because Im familiar with only half of whats in it I don't have the same apprehension plus due to my utter lack of a science background I throw my assumptions out the window about the components I've personally tried due to the fact it delivered through inhalation - that may be stupid of me or at minimum a very uninformed assumption that the outcomes could be drastically different.
I'd love it if the key to getting these ingredients where they need to be was the nebuliser factor paired with the ingredients having some reactive effect with each other.

cheers for your personal angle on it.

 

[wabi-sabi]

I'd love it if the key to getting these ingredients where they need to be was the nebuliser factor paired with the ingredients having some reactive effect with each other.

The nebulizer angle makes me even more suspicious. While most of us are short of breath, the problem generally isn't in our lungs. Nebulizers are used in diseases like asthma, where you want to get medication directly to the problem- the lungs. Our problem is our brains, immune systems, mitos, etc.

I take this to mean that the people making this med don't really understand our illness and are not thinking systemically about it.

 

[mitoMAN]

Does anyone have a list of whats in this stuff, i did a quick google search but came up empty.

Mainly anti-oxidants.

1. https://patents.google.com/patent/WO2021216749A1/en?inventor=George+Edward+Hoag&sort=new
   WO2021216749A1 - Method for treating viral and bacterial infection ...
   Liquid pharmaceutical liquid compositions that are orally administered and methods for their use by administration to the lungs for multifunctional treatment of lung and respiratory diseases.
   
   
   
   
   
   
2. A liquid pharmaceutical composition, comprising: 0.1 to 5 wt% 1,8-cineole; 0.1 to 2.5 wt% b-caryophyllene; 1.0 to 15 wt.% xylitol; 1.0 to 15 wt.% Polysorbate 20; 0.001 to 0.1 wt.% citric acid; 0.75 to 0.9 wt% sodium chloride; and 38 to 97.05 wt% sterile purified water.
   47. The liquid pharmaceutical composition of claim
   46, further comprising 0.1 to 5 wt% Af-acetyl cysteine; and 0.1 to 5 wt% glutathione.
   48. The liquid pharmaceutical composition of claim 46, further comprising: 0.001 to 1 wt% sodium bicarbonate; 0.00001 to 1 wt% L-theanine; 0.00001 to 1 wt% taurine; and 0.05 to 5.0 wt.% glycerol monolaurate.
   49. A liquid pharmaceutical composition, comprising: 1.0 wt% 1,8-cineole; 0.5 wt% b-caryophyllene; 5.0 wt.% xylitol; 1.0 wt.% Polysorbate 20; 0.07 wt.% citric acid; 8.23 wt% sodium chloride; 91.5 wt% sterile purified water.
   50. A method of treating an infectious viral or bacterial respiratory infection or disease of the upper respiratory tract by administering a liquid mist spray into a subject’s nostril, the liquid mist spray comprising: 0.1 to 5 wt% 1,8-cineole; 0.1 to 2.5 wt% b-caryophyllene; 1.0 to 15 wt.% xylitol; 1.0 to 15 wt.% Polysorbate 20; 0.001 to 0.1 wt.% citric acid; 0.75 to 0.9 wt% sodium chloride; and 38 to 97.05 wt% sterile purified water.
   51. The method of claim
   50, wherein the liquid mist spray further comprises: 0.1 to 5 wt% A-acetyl cysteine; and 0.1 to 5 wt% glutathione. 52. The method of claim 50, wherein the liquid mist spray comprises: 1.0 wt% 1,8-cineole; 0.5 wt% b-caryophyllene; 5.0 wt.% xylitol; 1.0 wt.% Polysorbate 20; 0.07 wt.% citric acid; 8.23 wt% sodium chloride; 91.5 wt% sterile purified water.

 

[Alvin2]

Mainly anti-oxidants.

1. https://patents.google.com/patent/WO2021216749A1/en?inventor=George+Edward+Hoag&sort=new
   WO2021216749A1 - Method for treating viral and bacterial infection ...
   Liquid pharmaceutical liquid compositions that are orally administered and methods for their use by administration to the lungs for multifunctional treatment of lung and respiratory diseases.
   
   
   
   
   
   
2. A liquid pharmaceutical composition, comprising: 0.1 to 5 wt% 1,8-cineole; 0.1 to 2.5 wt% b-caryophyllene; 1.0 to 15 wt.% xylitol; 1.0 to 15 wt.% Polysorbate 20; 0.001 to 0.1 wt.% citric acid; 0.75 to 0.9 wt% sodium chloride; and 38 to 97.05 wt% sterile purified water.
   47. The liquid pharmaceutical composition of claim
   46, further comprising 0.1 to 5 wt% Af-acetyl cysteine; and 0.1 to 5 wt% glutathione.
   48. The liquid pharmaceutical composition of claim 46, further comprising: 0.001 to 1 wt% sodium bicarbonate; 0.00001 to 1 wt% L-theanine; 0.00001 to 1 wt% taurine; and 0.05 to 5.0 wt.% glycerol monolaurate.
   49. A liquid pharmaceutical composition, comprising: 1.0 wt% 1,8-cineole; 0.5 wt% b-caryophyllene; 5.0 wt.% xylitol; 1.0 wt.% Polysorbate 20; 0.07 wt.% citric acid; 8.23 wt% sodium chloride; 91.5 wt% sterile purified water.
   50. A method of treating an infectious viral or bacterial respiratory infection or disease of the upper respiratory tract by administering a liquid mist spray into a subject’s nostril, the liquid mist spray comprising: 0.1 to 5 wt% 1,8-cineole; 0.1 to 2.5 wt% b-caryophyllene; 1.0 to 15 wt.% xylitol; 1.0 to 15 wt.% Polysorbate 20; 0.001 to 0.1 wt.% citric acid; 0.75 to 0.9 wt% sodium chloride; and 38 to 97.05 wt% sterile purified water.
   51. The method of claim
   50, wherein the liquid mist spray further comprises: 0.1 to 5 wt% A-acetyl cysteine; and 0.1 to 5 wt% glutathione. 52. The method of claim 50, wherein the liquid mist spray comprises: 1.0 wt% 1,8-cineole; 0.5 wt% b-caryophyllene; 5.0 wt.% xylitol; 1.0 wt.% Polysorbate 20; 0.07 wt.% citric acid; 8.23 wt% sodium chloride; 91.5 wt% sterile purified water.

So basically it's the kitchen sink approach. Throw everything at the problem and hope something works.

He also loves to write, I have read survival guides that are way shorter than that. Heck my whole website so far put together is likely much shorter then that.

 

[Wishful]

So basically it's the kitchen sink approach.

Well, the main ingredients 'smell nice' and probably trigger good memories of chest rubs or whatever. I know that eucalyptus/menthol triggers my childhood memories of 'loving care' for illness or owies (our medicine box had the nice smelly rub). Theanine and taurine are popular marketing tags, so they may have been thrown in purely for marketing purposes. Some of the other ingredients might be to counter the unpleasant effects of the other ingredients, the same way that toothpaste has multiple ingredients to counter the unpleasant aspects of putting soap and chalk in your mouth.

 

[Alvin2]

the same way that toothpaste has multiple ingredients to counter the unpleasant aspects of putting soap and chalk in your mouth.

By the time you read his 60,000 word patent application you will have forgotten the unpleasantness

I kid you not:
59,822 Words

423,325 Characters

361,967 Characters without space

117,072 Syllables

2,660 Sentences

1,328 Paragraphs

 

[YippeeKi YOW !!]

By the time you read his 60,000 word patent application you will have forgotten the unpleasantness

I kid you not:
59,822 Words

Finally !!!! Someone as mildly OCD as I am/

Kudos for the counting !!!!! And I think I'll skip the reading it part. Possibly unfairly, I've pretty much already made up my mid regarding the product's value, based on the information and links in this thread.

 

[Alvin2]

Finally !!!! Someone as mildly OCD as I am/

Thanks. I think

Kudos for the counting !!!!!

I like numbers even if i can't work them anymore.

 

[YippeeKi YOW !!]

Thanks. I think

Absolutely a compliment ....

I like numbers even if i can't work them anymore.

I have the same odd fixation on numbers .... I was paying two insurance policies by phone with my broker, because, you know, brain lapse, and when we went to the second poicy and I got the confirmation number, I noticed that some 420 other confirmation numbers had been issued in the 90 seconds it had taken between payment 1 and payment 2 ....

To my surprize, the broker who was handling this for me laughed and said, "I thought I was the only person who noticed that kind of thing ...."

So our numbers are greater than we thought .... INSERT EVIL LAUGH EMOJI, Which we definitely need one of .....

 

[EtherSpin]

Well, the main ingredients 'smell nice' and probably trigger good memories of chest rubs or whatever. I know that eucalyptus/menthol triggers my childhood memories of 'loving care' for illness or owies (our medicine box had the nice smelly rub). Theanine and taurine are popular marketing tags, so they may have been thrown in purely for marketing purposes. Some of the other ingredients might be to counter the unpleasant effects of the other ingredients, the same way that toothpaste has multiple ingredients to counter the unpleasant aspects of putting soap and chalk in your mouth.

Taurine I can't speak to but Theanine is no lightweight - its the reason Green tea hits so different to cup of coffee - no jitters, less chance of insomnia etc but I don't know what its job would be here.
its a great anxiolytic due to how safe it is to consume and above and beyond that is an antioxidant - does seem a weird one to select if you aren't making a supplement to chill people out.

 

[JenTheHen]

The nebulizer angle makes me even more suspicious. While most of us are short of breath, the problem generally isn't in our lungs. Nebulizers are used in diseases like asthma, where you want to get medication directly to the problem- the lungs. Our problem is our brains, immune systems, mitos, etc.

I take this to mean that the people making this med don't really understand our illness and are not thinking systemically about it.

 

[Dude]

I just wondered today what might have happened to this Inspiritol that was announced a long time ago; apparently, there are some updates and also related to T-cell dysfunction.

Preliminary results from a small, retrospectively assessed group treated with the novel agent Inspiritol, showed an improvement in CD8 T cell function that paralleled patient reports of reduced symptoms, including fatigue and cognitive difficulties over the course of treatment.

https://www.umassmed.edu/news/news-...ch-into-long-covid-myalgic-encephalomyelitis/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10847863/