New treatment being researched: Inspiritol—Today’s Press Release

[Sushi]

FAIRFIELD, Conn., Oct. 25, 2021/PRNewswire/ -- Inspiritol, Inc., a virtual pharmaceutical start-up filed a response with the FDA as part of their Investigational New Drug Application process for Inspiritol, a novel treatment for COVID-19, Long-COVID, and ME/CFS (Myalgic encephalomyelitis/chronic fatigue). Inspiritol is a nebulized inhaled multi-mechanism medication designed to treat the major symptoms of respiratory distress with anti-oxidant, anti-inflammatory, and broad spectrum anti-viral and anti-bacterial properties. Inspiritol is comprised of both endogenously produced and naturally occurring, well tolerated biochemicals co-developed by Dr. John P. Salerno, MD with a practice in New York City and George E. Hoag, Ph.D. Inspiritol, Inc. has several U.S. and foreign patent applications pending.

https://www.ksnblocal4.com/prnewswi...effective-covid-19-long-covid-mecfs-patients/

 

[ljimbo423]

A couple of quotes from the article-

Since 2018, Dr. Salerno treated patients diagnosed with COPD, Asthma, COVID-19, Long-COVID, and ME/CFS with Inspiritol. Inspiritol Inc. is seeking approval from the FDA to conduct human clinical trials on patients with COVID-19, Long-COVID and ME/CFS.

Dr. Salerno stated, "A hallmark of Inspiritol treated patients is a rapid increase of oxygen in their blood and decreases in fatigue and difficulty thinking, commonly referred to as 'brain fog'."

Dr. Liisa Selin, MD, Ph.D., Professor of Pathology and a specialist in infectious diseases and immunology with Anna Gil, Ph.D., both at UMass Chan Medical School have developed new methods to study biomarkers of chronic inflammatory diseases.

They discovered similarities in immune system responses of Long-COVID and ME/CFS patients, including CD8 T cell exhaustion, increased frequency of CD4+CD8+ T cells, and difficulty controlling persistent viral pathogens.

Dr. Selin said, "Our research findings could point to potential biomarkers, treatments and ways of tracking responses to therapies for Long-COVID and ME/CFS, methods that are immediately needed.

Our research indicates that individuals with Long-COVID and ME/CFS have biological abnormalities, including; oxidative stress imbalances, systemic inflammation and neuroinflammation."

Working with Dr. Salerno's patients, Dr. Selin and Dr. Gil ran these same biomarker tests on two with Long-COVID and one with ME/CFS and reported,

"We obtained dramatic improvement of these patients' symptoms associated with changes in their biomarkers without evidence of any significant side effects, including routine blood work, following continuous Inspiritol therapy from 2 to more than 5 months."

 

[Tammy]

From what I can gather, the product basically contains antioxidant/s and anti-inflammatory substance. I'm guessing Glutathione or NAC might be in it since they are both so good for the lungs. I know nebulized Glutathione is used for lung issues. Couldn't find actual ingredients.

 

[ljimbo423]

Couldn't find actual ingredients.

I couldn't either. I think their keeping that a well guarded secret for now.

 

[wabi-sabi]

I'm also curious what biomarkers they are using. There didn't seem to be details on that either.

 

[Rufous McKinney]

so its the delivery system? (they want to control?)

Why should NAC, glutathione....common supplements- be Trademarked or whatever we call this?

 

[Rufous McKinney]

what is antiviral/antibacterial about it?

 

[Wishful]

Why should NAC, glutathione....common supplements- be Trademarked or whatever we call this?

Secret recipe? Maybe if you mix 39.023% of one ingredient with 16.7718% of another, you can trademark it as a secret recipe. It doesn't have to be better than any other recipe, just unique.

 

[wabi-sabi]

what is antiviral/antibacterial about it?

And why would you want to inhale that?

 

[andyguitar]

Not much chance of getting a patent for it.

 

[Rufous McKinney]

why would you want to inhale that?

if viruses are occupying the olfactory bulb, maybe thats a good location to try to treat directly.

 

[Alvin2]

Inspiritol?

Did someone say inspirobot?

 

[Wishful]

The treatment inspires you to get better. Kind of like CBT.

 

[Rufous McKinney]

The treatment inspires you to get better. Kind of like CBT.

the treatment is inspiring me to get a nebulizer, and start making decoctions.

 

[Alvin2]

the treatment is inspiring me to get a nebulizer, and start making decoctions.

For some reason i read that as narcotics

 

[Rufous McKinney]

narcotic decoctions can be some of the best kind!

 

[Alvin2]

narcotic decoctions can be some of the best kind!

Indeed, especially for us income deprived ME/CFS patients

 

[EtherSpin]

The treatment inspires you to get better. Kind of like CBT.

I think I've missed a bit of something here - I saw one of the people using the combination of compounds referenced as being legit/ helpful on Reddit and thought I'd be able to find more clues on here but the tone is very different

besides the name being hokey - is there anything setting off alarm bells here when the supplement/drug itself is aiming to be a proper treatment and not a way of thinking about this illness like CBT ?

have I missed clue somewhere that we should automatically discount this ?

 

[Wishful]

have I missed clue somewhere that we should automatically discount this ?

I think many of us disregard it because it's just specific proportions of supplements many of us have already tried. Since ME varies so much between victims, it's highly unlikely that any precise and specific proportion of common supplements would work for many people while slightly different proportions wouldn't.

 

[Alvin2]

I think many of us disregard it because it's just specific proportions of supplements many of us have already tried.

Does anyone have a list of whats in this stuff, i did a quick google search but came up empty.