New B complex and itchy lower calves

[Gondwanaland]

I have had itchy lower calves for many years. Early this year when I started taking mB12 it just disappeared.

Early August I was taking the following B complex and having a break from mB12:

Thiamin HCl 10 mg
Riboflavin 5 mg
Nicotinamide 25 mg
Calcium pantothenate 50 mg
Pirydoxine HCl 30 mg
Biotin 500mcg

Aside from that I took some aminoacids and malic acid and had serious issues with salicylates. I took some baths with sodium bicarbonate and lots of magnesium oxide orally and recovered from the extreme sal intolerance.

Then three days ago I started this new B complex:

Thiamin HCl 15 mg
Riboflavin 5 mg
Niacin 15 mg
Calcium pantothenate 35 mg
P5P 10 mg
Biotin 300mcg
mB12 100 mcg
MgO 200mg

The same day I started taking it (1/2 at breakfast and 1/2 with the afternoon snack) the itchy lower calves came back with a vengeance... I can scratch them until bleeding...

Does anyone know this symptom? Is it lack of folate? Or some of the others B vits?

I have some folinic to try... I will start taking 20mcg of it each time I take the B complex. I just can't get over the trauma of taking methylfolate... Even if most part of the problem was probably due to overdoing with high salicylate foods an being unware of that a few month ago...

Any help will be greatly appreciated!

izzy

 

[Gloria H]

the itchy lower calves came back with a vengeance... I can scratch them until bleeding...
izzy

I've occasionally had this symptom occurring during night while asleep. I haven't nailed down a specific cause but suspected gluten, casein, sugar & ? or a combination of what have been my no no foods. I reach for 1 quercetin/bromelain & give it 30 min. to start relief. If I know I've gone beyond my safe foods, I take it before bed to avoid that histamine itch that I've experienced. Blessings to you!
Here's the one I use:
https://www.swansonvitamins.com/swanson-premium-quercetin-bromelain-250-78-mg-250-caps

 

[Critterina]

For me, itchy skin that won't respond to anything else is relieved by biotin. It takes 5-6 weeks after I run out before symptoms resume.
But since you were taking 500 then 0 then 300, and the problem started in going from 0 to 300, that doesn't seem to be likely the cause of your problem. Unless the break you took was 5-6 weeks and the timing is coincidence.
My first thought was, "what ELSE is in the pills?" Could it be the capsule or filler you're reacting to?
Let us know if the quercetin helps.

 

[UM MAN]

I have that reaction to Povidone (polyvinylpyrrolidone, PVP).

 

[Gondwanaland]

quercetin/bromelain

One month ago I started supplementing quercetin, bromelain and malic acid. That is when and how I found I am salicylate sensitive

coincidence

I don't believe in coincidences, and I think low biotin might be somehow implicated. I am sure I have been biotin deficient for many years now, I am even looking into biotinidase deficiency .
About something else added to my B complex, this is the first one I take with no excipients added, I asked the cmpd pharmacy to use only magnesium oxide as a filler. BUT:

I have that reaction to Povidone (polyvinylpyrrolidone, PVP).

UM MAN might be into something here... I have had this symptom for many years while taking a birth control pill which has povidone. But even after having stopped taking it the symptom went on for a couple of years. Stopped overnight with my first mB12 dose and now is back after one month taking citalopram which has is too.

I find if funny that it would reappear in the same day I restarted the mB12 and B7 at lower doses...

Now how do I convince my psychiatrist that I am better off the citalopram?

Thank you so much everyone for your input!

izzy

 

[Gondwanaland]

Following a homeopathic treatment with Sulphur turned my itchy flaky lower calves into history