https://www.sciencedaily.com/releases/2020/06/200615100929.htm
Summary:Exposure to air particulate matter impairs the metabolism of olfactory mucosal cells, according to a recent study. The results can contribute to a better understanding of how air pollutants may harm brain health, as the olfactory mucosa can act as a key pathway to the brain.
I noticed this: "The researchers also identified the mitochondria-targeted NPTX1 gene, which has been shown previously to be associated with brain disorders, as a key driver of mitochondrial dysfunction upon particulate matter exposure." Following that to wikigenes, I found:
Summary:Exposure to air particulate matter impairs the metabolism of olfactory mucosal cells, according to a recent study. The results can contribute to a better understanding of how air pollutants may harm brain health, as the olfactory mucosa can act as a key pathway to the brain.
I noticed this: "The researchers also identified the mitochondria-targeted NPTX1 gene, which has been shown previously to be associated with brain disorders, as a key driver of mitochondrial dysfunction upon particulate matter exposure." Following that to wikigenes, I found:
- Sema-3A/NP-1 interaction down-modulated T cell activation since addition of Sema-3A in DC/T cell cocultures dramatically inhibited allogeneic T cell proliferation [20].